Ethyl benzimidate hydrochloride, 97%
Ethyl benzimidate hydrochloride, 97%
Ethyl benzimidate hydrochloride, 97%
Thermo Scientific Chemicals

Ethyl benzimidate hydrochloride, 97%

CAS: 5333-86-8 | C9H12ClNO | 185.65 g/mol
Quantity:
10 g
50 g
Catalog number L17684.18
also known as L17684-18
Price (JPY)
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Quantity:
50 g
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Chemical Identifiers
CAS5333-86-8
SpecificationsSpecification SheetSpecification Sheet
FormCrystals or powder or crystalline powder
Appearance (Color)White
Assay (Titration ex Chloride)≥96.0 to ≤104.0%
Ethyl benzimidate hydrochloride is used in the preparation of (4R)-ethyl 2-phenyl-4,5-dihydrothiazole-4-carboxylate by reacting with (R)-ethyl cysteine hydrochloride. It also reacts with D-penicillamine methyl ester hydrochloride and triethylamine to prepare methyl-5,5- dimethyl-2-phenyl-2-thiazoline-4-carboxylate. Further, it is used as an intermediate for organic synthesis.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
Ethyl benzimidate hydrochloride is used in the preparation of (4R)-ethyl 2-phenyl-4,5-dihydrothiazole-4-carboxylate by reacting with (R)-ethyl cysteine hydrochloride. It also reacts with D-penicillamine methyl ester hydrochloride and triethylamine to prepare methyl-5,5- dimethyl-2-phenyl-2-thiazoline-4-carboxylate. Further, it is used as an intermediate for organic synthesis.

Solubility
Soluble in water.

Notes
Incompatible with strong oxidizing agents.
RUO – Research Use Only

General References:

  1. Schmidt, M. A.; Qian, X. A mild synthesis of [1,2,4]triazolo[4,3-a]pyridines. Tetrahedron Lett. 2013, 54 (42), 5721-5726.
  2. Johnston, H. J.; Hulme, A. N. A Facile, Inexpensive and Scalable Route to Thiol Protected alpha-Methyl Cysteine. Synlett 2013, 24 (5), 591-594.