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Thermo Scientific Chemicals
N-Boc-1,6-diaminohexane, 98%
CAS: 51857-17-1 | C11H24N2O2 | 216.325 g/mol
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Chemical Identifiers
CAS51857-17-1
IUPAC Nametert-butyl N-(6-azaniumylhexyl)carbamate
Molecular FormulaC11H25N2O2
InChI KeyRVZPDKXEHIRFPM-UHFFFAOYSA-O
SMILESCC(C)(C)OC(=O)NCCCCCC[NH3+]
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Specifications
Specification Sheet
Specification SheetAssay (GC)≥97.5%
Refractive Index1.4585-1.4625 @ 20?C
Appearance (Color)Clear colorless to pale yellow
FormLiquid or viscous liquid
Assay (Non-aqueous acid-base Titration)≥97.5 to ≤102.5%
N-Boc-1,6-diaminohexane is used to prepare 1,3-Bis[6-(Boc-amino)hexyl]urea by reacting with carbonyl dichloride in the presence of triethylamine. Further, it is used as a reagent for the introduction of a C6-spacer.
This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.
Applications
N-Boc-1,6-diaminohexane is used to prepare 1,3-Bis[6-(Boc-amino)hexyl]urea by reacting with carbonyl dichloride in the presence of triethylamine. Further, it is used as a reagent for the introduction of a C6-spacer.
Solubility
Soluble in dichloromethane and ethyl acetate.
Notes
Air sensitive. Incompatible with strong oxidizing agents.
N-Boc-1,6-diaminohexane is used to prepare 1,3-Bis[6-(Boc-amino)hexyl]urea by reacting with carbonyl dichloride in the presence of triethylamine. Further, it is used as a reagent for the introduction of a C6-spacer.
Solubility
Soluble in dichloromethane and ethyl acetate.
Notes
Air sensitive. Incompatible with strong oxidizing agents.
RUO – Research Use Only
General References:
- Jong, T.; Bradley, M. Flow-Mediated Synthesis of Boc, Fmoc, and Ddiv Monoprotected Diamines. Org. Lett. 2015, 17 (3), 422-425.
- Jong, T.; Pérez-López, A. M.; Johansson, E. M. V.; Lilienkampf, A.; Bradley, M. Flow and Microwave-Assisted Synthesis of N-(Triethylene glycol)glycine Oligomers and Their Remarkable Cellular Transporter Activities. Bioconjugate Chem. 2015, 26 (8), 1759-1765.