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Citations & References (14)
Invitrogen™
Qdot™ 605 ITK™ Carboxyl Quantum Dots
Qdot™ 605 ITK™ carboxyl quantum dots are the ideal starting material for preparing custom conjugates that require high loading ofRead more
| Catalog Number | Quantity |
|---|---|
| Q21301MP | 250 μL |
Catalog number Q21301MP
Price (JPY)Contact Us ›
89,200
Each
Quantity:
250 μL
Qdot™ 605 ITK™ carboxyl quantum dots are the ideal starting material for preparing custom conjugates that require high loading of biomolecules. These materials are carboxylate functionalized and can be coupled to amine groups of proteins and modified oligonucleotides using EDC-mediated condensation. The coatings of these probes provides more binding sites than our Qdot™ ITK™ amino quantum dots, but lacks PEG linkers that help to prevent non-specific interactions. These materials can be conjugated to X-PEG-amine bi-functional linkers for custom reactivity and higher specificity. Our Qdot™ ITK™ carboxyl quantum dots are provided as 8 μM solutions and are available in all 9 Qdot™ probe colors.
Important Features of Qdot™ ITK™ Carboxyl Quantum Dots:
• Qdot™ 605 ITK™ carboxyl quantum dot has emission maxima of ∼605 nm
• Extremely photostable and bright fluorescence
• Efficiently excited with single-line excitation sources
• Narrow emission, large Stokes shift
• Available in multiple colors
• Ideal labeling and tracking applications
Properties of Qdot™ Nanocrystals
Qdot™ probes are ideal for imaging and labeling applications that require bright fluorescent signals and/or real-time tracking. Unique among fluorescent reagents, all nine available colors of Qdot™ probes can be simultaneously excited with a single (UV to blue-green) light source. This property makes these reagents excellent for economical and user-friendly multiplexing applications. Qdot™ labels are based on semiconductor nanotechnology and are similar in scale to moderately sized proteins.
About the Innovator’s Tool Kit Qdot™ ITK™ Reagents
These Qdot™ ITK™ probes are ideal for researchers who wish to prepare specific (non-stocked) conjugates for their applications and need customizable conjugation functionality.
Other Forms of Qdot™ Nanocrystals are Available
In addition to the carboxyl-derivatized form, we offer Qdot™ ITK™ quantum dots with amino and aliphatic hydrocarbon modifications. We’ve also developed a wide range of Qdot™ nanocrystals conjugates and labeling kits. Investigate the properties of Qdot™ nanocrystals or read the Molecular Probes™ Handbook Section 6.6—Qdot™ Nanocrystals to find out more.
For Research Use Only. Not intended for any animal or human therapeutic or diagnostic use.
Important Features of Qdot™ ITK™ Carboxyl Quantum Dots:
• Qdot™ 605 ITK™ carboxyl quantum dot has emission maxima of ∼605 nm
• Extremely photostable and bright fluorescence
• Efficiently excited with single-line excitation sources
• Narrow emission, large Stokes shift
• Available in multiple colors
• Ideal labeling and tracking applications
Properties of Qdot™ Nanocrystals
Qdot™ probes are ideal for imaging and labeling applications that require bright fluorescent signals and/or real-time tracking. Unique among fluorescent reagents, all nine available colors of Qdot™ probes can be simultaneously excited with a single (UV to blue-green) light source. This property makes these reagents excellent for economical and user-friendly multiplexing applications. Qdot™ labels are based on semiconductor nanotechnology and are similar in scale to moderately sized proteins.
About the Innovator’s Tool Kit Qdot™ ITK™ Reagents
These Qdot™ ITK™ probes are ideal for researchers who wish to prepare specific (non-stocked) conjugates for their applications and need customizable conjugation functionality.
Other Forms of Qdot™ Nanocrystals are Available
In addition to the carboxyl-derivatized form, we offer Qdot™ ITK™ quantum dots with amino and aliphatic hydrocarbon modifications. We’ve also developed a wide range of Qdot™ nanocrystals conjugates and labeling kits. Investigate the properties of Qdot™ nanocrystals or read the Molecular Probes™ Handbook Section 6.6—Qdot™ Nanocrystals to find out more.
For Research Use Only. Not intended for any animal or human therapeutic or diagnostic use.
For Research Use Only. Not for use in diagnostic procedures.
Specifications
Chemical ReactivityAmine
Concentration8 μM
Emission605
Label or DyeQdot™ 605
Product TypeQuantum Dot
Quantity250 μL
Reactive MoietyCarboxylic Acid
Shipping ConditionRoom Temperature
Label TypeQdot Nanocrystals
Product LineITK, Qdot
Unit SizeEach
Contents & Storage
Store in refrigerator (2–8°C).
Frequently asked questions (FAQs)
How large are the Qdot nanocrystals?
What is the best way to remove white precipitate from my ITK Qdot nanocrystals?
I see a white precipitate in my ITK Qdot nanocrystals; should I be concerned?
Why do my Qdot nanocrystals appear to be blinking?
My Qdot nanocrystals were brightly fluorescent before I mounted my samples; now I'm seeing a loss of fluorescence. Why is this happening?
Citations & References (14)
Citations & References
Abstract
Binding of muscimol-conjugated quantum dots to GABAC receptors.
Journal:J Am Chem Soc
PubMed ID:17147380
'Functionalization of highly fluorescent CdSe/ZnS core-shell nanocrystals (quantum dots, qdots) is an emerging technology for labeling cell surface proteins. We have synthesized a conjugate consisting of approximately 150-200 muscimols (a GABA receptor agonist) covalently joined to the qdot via a poly(ethylene glycol) (PEG) linker (approximately 78 ethylene glycol units) and
Fluorescent cell barcoding in flow cytometry allows high-throughput drug screening and signaling profiling.
Journal:Nat Methods
PubMed ID:16628206
'Flow cytometry allows high-content, multiparameter analysis of single cells, making it a promising tool for drug discovery and profiling of intracellular signaling. To add high-throughput capacity to flow cytometry, we developed a cell-based multiplexing technique called fluorescent cell barcoding (FCB). In FCB, each sample is labeled with a different signature,
Water-soluble quantum dots for multiphoton fluorescence imaging in vivo.
Journal:Science
PubMed ID:12775841
'The use of semiconductor nanocrystals (quantum dots) as fluorescent labels for multiphoton microscopy enables multicolor imaging in demanding biological environments such as living tissue. We characterized water-soluble cadmium selenide-zinc sulfide quantum dots for multiphoton imaging in live animals. These fluorescent probes have two-photon action cross sections as high as 47,000
The dynamic control of kiss-and-run and vesicular reuse probed with single nanoparticles.
Journal:Science
PubMed ID:19213879
'Vesicular secretion of neurotransmitter is essential for neuronal communication. Kiss-and-run is a mode of membrane fusion and retrieval without the full collapse of the vesicle into the plasma membrane and de novo regeneration. The importance of kiss-and-run during efficient neurotransmission has remained in doubt. We developed an approach for loading
Targeted tumor cell internalization and imaging of multifunctional quantum dot-conjugated immunoliposomes in vitro and in vivo.
Journal:Nano Lett
PubMed ID:18712930
'Targeted drug delivery systems that combine imaging and therapeutic modalities in a single macromolecular construct may offer advantages in the development and application of nanomedicines. To incorporate the unique optical properties of luminescent quantum dots (QDs) into immunoliposomes for cancer diagnosis and treatment, we describe the synthesis, biophysical characterization, tumor