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인용 및 참조 문헌 (4)
Thermo Scientific™
BMH (bismaleimidohexane)
Thermo Scientific Pierce BMH is a long-arm, maleimide crosslinker for covalent, irreversible conjugation between sulfhydryl groups (e.g., protein or peptide자세히 알아보기
| 카탈로그 번호 | 수량 |
|---|---|
| 22330 | 50 mg |
카탈로그 번호 22330
제품 가격(KRW)
206,000
온라인 행사
Ends: 31-Mar-2026
1,392,000할인액 1,186,000 (85%)
Each
수량:
50 mg
제품 가격(KRW)
206,000
온라인 행사
Ends: 31-Mar-2026
1,392,000할인액 1,186,000 (85%)
Each
Thermo Scientific Pierce BMH is a long-arm, maleimide crosslinker for covalent, irreversible conjugation between sulfhydryl groups (e.g., protein or peptide cysteines).
Features of BMH:
• Reactive groups: maleimide (both ends)
• Reactive towards: sulfhydryl groups
• Long (13.0Å), sulfhydryl-to-sulfhydryl crosslinker, composed of maleimide groups and 11-atom spacer arm
• Water-insoluble—dissolve first in DMF or DMSO, then add to aqueous reaction buffers
• Noncleavable
Crosslinker Application Guide -- search for recent literature references for this product
Related Products
BMB (1,4-bismaleimidobutane)
BMOE (bismaleimidoethane)
BM(PEG)2 (1,8-bismaleimido-diethyleneglycol)
BM(PEG)3 (1,11-bismaleimido-triethyleneglycol)
Features of BMH:
• Reactive groups: maleimide (both ends)
• Reactive towards: sulfhydryl groups
• Long (13.0Å), sulfhydryl-to-sulfhydryl crosslinker, composed of maleimide groups and 11-atom spacer arm
• Water-insoluble—dissolve first in DMF or DMSO, then add to aqueous reaction buffers
• Noncleavable
Crosslinker Application Guide -- search for recent literature references for this product
Related Products
BMB (1,4-bismaleimidobutane)
BMOE (bismaleimidoethane)
BM(PEG)2 (1,8-bismaleimido-diethyleneglycol)
BM(PEG)3 (1,11-bismaleimido-triethyleneglycol)
For Research Use Only. Not for use in diagnostic procedures.
사양
세포 투과성Yes
설명BMH
형태Powder
라벨링 방법Chemical Labeling
분자량276.29
페길레이티드No
제품라인Pierce
수량50 mg
반응성 부분Maleimide
배송 조건Ambient
용해도DMF, DMSO
스페이서 암 길이13.0 Å
수용성No
화학물질 반응성Sulfhydryl-Sulfhydryl
CleavableNo
교차결합제 유형Homobifunctional
형식Standard
제품 유형Crosslinker
스페이서Medium (10 to 30 Å)
Unit SizeEach
구성 및 보관
Upon receipt store at 4°C.
자주 묻는 질문(FAQ)
Can you provide the shelf-life for BMH (bismaleimidohexane)?
인용 및 참조 문헌 (4)
인용 및 참조 문헌
Abstract
Membrane curvature induced by Arf1-GTP is essential for vesicle formation.
Journal:Proc Natl Acad Sci U S A
PubMed ID:18689681
'The GTPase Arf1 is considered as a molecular switch that regulates binding and release of coat proteins that polymerize on membranes to form transport vesicles. Here, we show that Arf1-GTP induces positive membrane curvature and find that the small GTPase can dimerize dependent on GTP. Investigating a possible link between
The MUC1-C oncoprotein binds to the BH3 domain of the pro-apoptotic BAX protein and blocks BAX function.
Journal:J Biol Chem
PubMed ID:22544745
'The pro-apoptotic BAX protein contains a BH3 domain that is necessary for its dimerization and for activation of the intrinsic apoptotic pathway. The MUC1 (mucin 1) heterodimeric protein is overexpressed in diverse human carcinomas and blocks apoptosis in the response to stress. In this study, we demonstrate that the oncogenic
Two translocating hydrophilic segments of a nascent chain span the ER membrane during multispanning protein topogenesis.
Journal:J Cell Biol
PubMed ID:18166653
During protein integration into the endoplasmic reticulum, the N-terminal domain preceding the type I signal-anchor sequence is translocated through a translocon. By fusing a streptavidin-binding peptide tag to the N terminus, we created integration intermediates of multispanning membrane proteins. In a cell-free system, N-terminal domain (N-domain) translocation was arrested by
Resveratrol induces p53-independent, X-linked inhibitor of apoptosis protein (XIAP)-mediated Bax protein oligomerization on mitochondria to initiate cytochrome c release and caspase activation.
Journal:J Biol Chem
PubMed ID:21712378
Resveratrol, a naturally occurring phytoalexin, is known to induce apoptosis in multiple cancer cell types, but the underlying molecular mechanisms remain unclear. Here, we show that resveratrol induced p53-independent, X-linked inhibitor of apoptosis protein (XIAP)-mediated translocation of Bax to mitochondria where it underwent oligomerization to initiate apoptosis. Resveratrol treatment promoted