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          System Message

          OKCancel
          LOADING ...
          Gene:
          BRCA1
          Transcript:
          NM_007294.3
          Assay Name:
          Mutation genome location:
          chr.17 43093105-43093699 on build GRCh38
          Assay transcription exon location:
          Within Exon 10
          Assay ID Hs00447449_CE

          Purification
          Size
          Availability Made To Order
          Catalog # A15629
          Price
          Your Price
          Online offer:
          Check your price ›
          • Genomic Map
          • Assay Details
          • More Information

          Genomic Map

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          Assay Details


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          More Information


          Set Membership:

          Between 400-700 bp

          Panther Classification:

          Molecular Function -

          ubiquitin-protein ligase protein modifying enzyme

          Gene Ontology Categories:

          Function(s) Process(es)

          double-strand break repair via homologous recombination
          DNA double-strand break processing
          DNA synthesis involved in DNA repair
          strand displacement
          DNA replication
          postreplication repair
          double-strand break repair
          double-strand break repair via nonhomologous end joining
          regulation of gene expression by genetic imprinting
          transcription, DNA-templated
          regulation of transcription from RNA polymerase II promoter
          regulation of transcription from RNA polymerase III promoter
          fatty acid biosynthetic process
          apoptotic process
          cellular response to DNA damage stimulus
          DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator
          chromosome segregation
          centrosome cycle
          brain development
          response to nutrient
          intrinsic apoptotic signaling pathway in response to DNA damage
          dosage compensation by inactivation of X chromosome
          response to ionizing radiation
          positive regulation of vascular endothelial growth factor production
          positive regulation of gene expression
          protein ubiquitination
          protein sumoylation
          androgen receptor signaling pathway
          chromosome breakage
          positive regulation of protein ubiquitination
          G2 DNA damage checkpoint
          response to estradiol
          negative regulation of intracellular estrogen receptor signaling pathway
          positive regulation of protein import into nucleus, translocation
          positive regulation of histone acetylation
          negative regulation of histone acetylation
          regulation of cell proliferation
          regulation of apoptotic process
          chordate embryonic development
          response to estrogen
          regulation of DNA methylation
          negative regulation of fatty acid biosynthetic process
          positive regulation of DNA repair
          positive regulation of angiogenesis
          negative regulation of transcription, DNA-templated
          positive regulation of transcription, DNA-templated
          positive regulation of transcription from RNA polymerase II promoter
          negative regulation of centriole replication
          positive regulation of histone H3-K4 methylation
          negative regulation of histone H3-K4 methylation
          negative regulation of histone H3-K9 methylation
          positive regulation of histone H3-K9 methylation
          protein autoubiquitination
          positive regulation of histone H4-K20 methylation
          positive regulation of cell cycle arrest
          cellular response to tumor necrosis factor
          cellular response to indole-3-methanol
          protein K6-linked ubiquitination
          regulation of signal transduction by p53 class mediator
          negative regulation of extrinsic apoptotic signaling pathway via death domain receptors
          negative regulation of reactive oxygen species metabolic process
          positive regulation of histone H3-K9 acetylation
          positive regulation of histone H4-K16 acetylation
          DNA binding
          chromatin binding
          damaged DNA binding
          transcription coactivator activity
          RNA binding
          ubiquitin-protein transferase activity
          protein binding
          zinc ion binding
          tubulin binding
          ligase activity
          enzyme binding
          ubiquitin protein ligase binding
          transcription regulatory region DNA binding
          androgen receptor binding

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          Host server : magellan-search-blue-67655d8755-vzwvz:80/100.66.79.173:80.
          git-commit: dddaa802cd395f65bf1581942d0e97a089c38f41
          git-url: https://github.com/thermofisher/magellan-search
          git-branch: release/2.46.0-Offline