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          • Home
          • › Search Tool
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          • › Hs01645664_cn
          See other ILK CNV Assays ›
          Gene Symbol
          ILK
          Assay Reference Genome
          Location

          Chr.11:6608896 on build GRCh38
          Cytoband
          11p15.4
          Assay ID Hs01645664_cn
          Size
          Availability Made To Order
          Catalog # 4400291
          Price
          Your Price
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          • Genomic Map
          • Assay Details
          • More Information

          Genomic Map

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          Assay Details

          Target Gene Details

          Entrez Gene ID:

          3611

          Gene Name:

          integrin linked kinase

          Gene Aliases:

          HEL-S-28, ILK-1, ILK-2, P59, p59ILK

          Location:

          Chr.11:6603708-6610874 on Build GRCh38

          Assay Gene Location:

          Overlaps Intron 4 - Exon 5
          Gene Symbol Transcript Accession Exon Location Assay Transcript Location Protein ID
          ILK NM_001014794.2 NP_001014794.1
          NM_001014795.2 NP_001014795.1
          NM_001278441.1 NP_001265370.1
          NM_001278442.1 NP_001265371.1
          NM_004517.3 NP_004508.1
          XM_005252904.4 XP_005252961.1
          XM_005252905.2 XP_005252962.1
          XM_011520065.1 XP_011518367.1
          XM_017017672.1 XP_016873161.1
          AB209416.1 1 5087 BAD92653.1
          AK293474.1
          AK296628.1
          AK314843.1 5 696
          BC001554.1 AAH01554.1
          CR407673.1 CAG28601.1
          CR749220.1 CAH18077.1
          EU794625.1
          U40282.1 AAC16892.1

          Target Copy Number Variation Details

          DGV Version:

          Release date: 2016-05-15, GRCh GRCh38
          Target
          Variation
          Location CNV
          Subtype
          Genes
          nsv553373 Chr.11:6601484 - 6647097 on Build GRCh38 Loss ILK TAF10 DCHS1 RRP8 TPP1
          nsv1035138 Chr.11:6607812 - 6980555 on Build GRCh38 Gain TAF10 OR2AG1 OR2D2 DCHS1 OR10A2 OR10A5 GVINP1 ILK OR2AG2 MRPL17 OR6A2 OR2D3 TPP1 ZNF215 OR10A4
          esv996362 Chr.11:6597567 - 6612421 on Build GRCh38 Deletion ILK TAF10 RRP8
          nsv825755 Chr.11:6591998 - 6656613 on Build GRCh38 Gain ILK TAF10 DCHS1 RRP8 TPP1

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          More Information


          Set Membership:

          Intragenic Non-exonic DGV Variation

          Panther Classification:

          Molecular Function -

          non-receptor serine/threonine protein kinase

          Gene Ontology Categories:

          Function(s) Process(es)

          branching involved in ureteric bud morphogenesis
          positive regulation of cell-matrix adhesion
          outflow tract morphogenesis
          protein phosphorylation
          negative regulation of protein kinase activity
          cell cycle arrest
          cell-matrix adhesion
          integrin-mediated signaling pathway
          cell aging
          cell proliferation
          positive regulation of cell proliferation
          negative regulation of cardiac muscle cell apoptotic process
          fibroblast migration
          negative regulation of smooth muscle cell migration
          peptidyl-serine phosphorylation
          nerve development
          myelination in peripheral nervous system
          positive regulation of cell migration
          positive regulation of BMP signaling pathway
          myelin assembly
          regulation of actin cytoskeleton organization
          cell junction assembly
          substrate adhesion-dependent cell spreading
          positive regulation of phosphorylation
          extracellular fibril organization
          positive regulation of MAP kinase activity
          protein kinase B signaling
          negative regulation of neuron apoptotic process
          establishment or maintenance of epithelial cell apical/basal polarity
          positive regulation of myoblast differentiation
          positive regulation of osteoblast differentiation
          positive regulation of axon extension
          positive regulation of transcription, DNA-templated
          negative regulation of smooth muscle cell proliferation
          neuron projection morphogenesis
          positive regulation of dendrite morphogenesis
          protein heterooligomerization
          positive regulation of protein kinase B signaling
          platelet aggregation
          positive regulation of canonical Wnt signaling pathway
          negative regulation of neural precursor cell proliferation
          protein serine/threonine kinase activity
          signal transducer activity
          integrin binding
          protein binding
          ATP binding
          SH3 domain binding
          protein kinase binding

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