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          • Home
          • › Search Tool
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          • › Hs02229422_cn
          See other HDAC6 CNV Assays ›
          Gene Symbol
          HDAC6
          Assay Reference Genome
          Location

          Chr.X:48823084 on build GRCh38
          Cytoband
          Xp11.23
          Assay ID Hs02229422_cn
          Size
          Availability Made To Order
          Catalog # 4400291
          Price
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          Online offer:
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          • Genomic Map
          • Assay Details
          • More Information

          Genomic Map

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          Assay Details

          Target Gene Details

          Entrez Gene ID:

          10013

          Gene Name:

          histone deacetylase 6

          Gene Aliases:

          CPBHM, HD6, JM21, PPP1R90

          Location:

          Chr.X:48801377-48824982 on Build GRCh38

          Assay Gene Location:

          Within Exon 24
          Gene Symbol Transcript Accession Exon Location Assay Transcript Location Protein ID
          HDAC6 NM_001321225.1 26 2841 NP_001308154.1
          NM_001321226.1 25 3251 NP_001308155.1
          NM_001321227.1 25 2972 NP_001308156.1
          NM_001321228.1 25 2935 NP_001308157.1
          NM_001321229.1 25 2789 NP_001308158.1
          NM_006044.3 25 2842 NP_006035.2
          NR_135591.1 23 2522
          AB020708.1 25 2757
          AF132609.1 24 2685 AAD29048.1
          AF174499.1 19 2239 AAF36540.1
          AJ011972.1 25 2778 CAA09893.1
          AK001543.1 9 1227
          AK024083.1
          AK095124.1 14 1778
          AK122954.1 13 2236
          AK127118.1 13 3391
          AK131286.1 3 1156
          AK302926.1 25 2780
          AK303012.1 23 2683
          AL137696.1 24 3502 CAB70878.2
          BC013737.1 24 2667 AAH13737.1
          BC069243.1 25 2784 AAH69243.1

          Target Copy Number Variation Details

          DGV Version:

          Release date: 2016-05-15, GRCh GRCh38
          Target
          Variation
          Location CNV
          Subtype
          Genes
          nsv528292 Chr.X:48433286 - 49274368 on Build GRCh38 Gain PIM2 EBP FTSJ1 PRAF2 GPKOW FOXP3 RBM3 PRICKLE3 TBC1D25 PLP2 SLC38A5 TFE3 OTUD5 CCDC22 PPP1R3F SLC35A2 LOC101927635 WDR13 GLOD5 GATA1 SYP PCSK1N MAGIX WDR45 PORCN CACNA1F TIMM17B SUV39H1 KCND1 SYP-AS1 HDAC6 PQBP1 ERAS GRIPAP1 WAS CCDC120
          esv32909 Chr.X:48003374 - 49285646 on Build GRCh38 Gain+Loss PIM2 SPACA5B EBP FTSJ1 PRAF2 GPKOW FOXP3 RBM3 PRICKLE3 TBC1D25 PLP2 SLC38A5 SSX4 TFE3 OTUD5 CCDC22 PPP1R3F SLC35A2 ZNF630-AS1 LOC101927635 WDR13 GLOD5 GATA1 SSX5 SYP PCSK1N MAGIX WDR45 PORCN CACNA1F SSX6 TIMM17B SSX4B SUV39H1 SSX9 KCND1 ZNF630 SYP-AS1 HDAC6 PQBP1 SSX3 ZNF182 SSX1 ERAS GRIPAP1 SPACA5 WAS CCDC120
          esv3576862 Chr.X:48755018 - 48837713 on Build GRCh38 Gain PCSK1N ERAS GLOD5 GATA1 HDAC6

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          More Information


          Set Membership:

          Intragenic Exonic DGV Variation

          Gene Ontology Categories:

          Function(s) Process(es)

          protein polyubiquitination
          transcription, DNA-templated
          protein deacetylation
          misfolded or incompletely synthesized protein catabolic process
          intracellular protein transport
          organelle organization
          negative regulation of microtubule depolymerization
          response to toxic substance
          positive regulation of signal transduction
          response to organic substance
          regulation of receptor activity
          regulation of autophagy
          positive regulation of epithelial cell migration
          negative regulation of hydrogen peroxide metabolic process
          positive regulation of receptor biosynthetic process
          macroautophagy
          histone deacetylation
          regulation of protein stability
          lysosome localization
          peptidyl-lysine deacetylation
          cellular response to topologically incorrect protein
          regulation of gene expression, epigenetic
          ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway
          protein complex disassembly
          negative regulation of protein complex disassembly
          regulation of fat cell differentiation
          negative regulation of proteolysis
          negative regulation of transcription, DNA-templated
          negative regulation of oxidoreductase activity
          mitochondrion localization
          response to misfolded protein
          regulation of microtubule-based movement
          regulation of androgen receptor signaling pathway
          regulation of establishment of protein localization
          cellular response to hydrogen peroxide
          aggresome assembly
          polyubiquitinated misfolded protein transport
          Hsp90 deacetylation
          response to growth factor
          histone H3 deacetylation
          cellular response to misfolded protein
          positive regulation of chaperone-mediated protein complex assembly
          tubulin deacetylation
          mitophagy in response to mitochondrial depolarization
          positive regulation of hydrogen peroxide-mediated programmed cell death
          regulation of mitophagy
          core promoter binding
          actin binding
          histone deacetylase activity
          protein binding
          beta-catenin binding
          microtubule binding
          zinc ion binding
          enzyme binding
          polyubiquitin binding
          ubiquitin protein ligase binding
          NAD-dependent histone deacetylase activity (H3-K14 specific)
          histone deacetylase binding
          tubulin deacetylase activity
          alpha-tubulin binding
          tau protein binding
          beta-tubulin binding
          misfolded protein binding
          Hsp90 protein binding
          dynein complex binding

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