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          • Home
          • › Search Tool
          • › Search Results
          • › Hs03657163_cn
          See other DLC1 CNV Assays ›
          Gene Symbol
          DLC1
          Assay Reference Genome
          Location

          Chr.8:13386490 on build GRCh38
          Cytoband
          8p22
          Assay ID Hs03657163_cn
          Size
          Availability Made To Order
          Catalog # 4400291
          Price
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          • Genomic Map
          • Assay Details
          • More Information

          Genomic Map

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          Assay Details

          Target Gene Details

          Entrez Gene ID:

          10395

          Gene Name:

          DLC1 Rho GTPase activating protein

          Gene Aliases:

          ARHGAP7, HP, STARD12, p122-RhoGAP

          Location:

          Chr.8:13083361-13604606 on Build GRCh38

          Assay Gene Location:

          Within Intron 6
          Gene Symbol Transcript Accession Exon Location Assay Transcript Location Protein ID
          DLC1 NM_024767.3 NP_079043.3
          NM_182643.2 NP_872584.2
          XM_005273374.1 XP_005273431.1
          XM_017012951.1 XP_016868440.1
          AB051510.1
          AK024773.1 BAB14996.1
          AK225098.1
          AK291682.1
          BC049842.1 AAH49842.1
          BC054511.1 AAH54511.1

          Target Copy Number Variation Details

          DGV Version:

          Release date: 2016-05-15, GRCh GRCh38
          Target
          Variation
          Location CNV
          Subtype
          Genes
          nsv610412 Chr.8:13121891 - 13662651 on Build GRCh38 Gain LOC102725080 DLC1 LOC101930149 C8orf48
          nsv8290 Chr.8:13234049 - 13677278 on Build GRCh38 Gain LOC102725080 DLC1 LOC101930149 C8orf48
          esv3891343 Chr.8:13293446 - 13473131 on Build GRCh38 Gain DLC1 LOC101930149
          esv3616309 Chr.8:13376895 - 13391937 on Build GRCh38 Loss DLC1
          nsv610411 Chr.8:13093516 - 14267300 on Build GRCh38 Loss SGCZ LOC102725080 DLC1 LOC101930149 C8orf48
          esv3616308 Chr.8:13356392 - 13476058 on Build GRCh38 Gain DLC1 LOC101930149
          nsv1022834 Chr.8:13067043 - 14121780 on Build GRCh38 Gain SGCZ LOC102725080 DLC1 LOC101930149 C8orf48
          esv3616305 Chr.8:13312741 - 13394970 on Build GRCh38 Gain DLC1 LOC101930149
          esv2752209 Chr.8:13367297 - 13460740 on Build GRCh38 Loss DLC1

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          More Information


          Set Membership:

          Intragenic Intronic Non-exonic DGV Variation

          Panther Classification:

          Molecular Function -

          G-protein modulator protein-binding activity modulator GTPase-activating protein

          Gene Ontology Categories:

          Function(s) Process(es)

          neural tube closure
          heart morphogenesis
          apoptotic process
          activation of cysteine-type endopeptidase activity involved in apoptotic process
          signal transduction
          negative regulation of cell proliferation
          regulation of cell shape
          hindbrain morphogenesis
          actin cytoskeleton organization
          negative regulation of cell migration
          forebrain development
          regulation of actin cytoskeleton organization
          negative regulation of Rho protein signal transduction
          positive regulation of protein dephosphorylation
          positive regulation of GTPase activity
          focal adhesion assembly
          regulation of small GTPase mediated signal transduction
          negative regulation of stress fiber assembly
          negative regulation of focal adhesion assembly
          positive regulation of execution phase of apoptosis
          GTPase activator activity
          protein binding
          lipid binding
          SH2 domain binding

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