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          • Home
          • › Search Tool
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          • › Hs04886071_cn
          See other MAP3K4 CNV Assays ›
          Gene Symbol
          MAP3K4
          Assay Reference Genome
          Location

          Chr.6:161067804 on build GRCh38
          Cytoband
          6q26
          Assay ID Hs04886071_cn
          Size
          Availability Made To Order
          Catalog # 4400291
          Price
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          • Genomic Map
          • Assay Details
          • More Information

          Genomic Map

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          Assay Details

          Target Gene Details

          Entrez Gene ID:

          4216

          Gene Name:

          mitogen-activated protein kinase kinase kinase 4

          Gene Aliases:

          MAPKKK4, MEKK 4, MEKK4, MTK1, PRO0412

          Location:

          Chr.6:160991521-161117385 on Build GRCh38

          Assay Gene Location:

          Within Intron 5
          Gene Symbol Transcript Accession Exon Location Assay Transcript Location Protein ID
          MAP3K4 NM_001291958.1 NP_001278887.1
          NM_001301072.1 NP_001288001.1
          NM_005922.3 NP_005913.2
          NM_006724.3 NP_006715.2
          NR_120425.1
          XM_005266989.2 XP_005267046.1
          XM_017010869.1 XP_016866358.1
          AF002715.1 AAB68804.1
          AK307866.1
          BC136276.1
          BC143735.1
          BC146770.1
          D86968.2

          Target Copy Number Variation Details

          DGV Version:

          Release date: 2016-05-15, GRCh GRCh38
          Target
          Variation
          Location CNV
          Subtype
          Genes
          esv3611453 Chr.6:160930783 - 161147021 on Build GRCh38 Gain AGPAT4 MAP3K4
          esv3576242 Chr.6:160924181 - 161141222 on Build GRCh38 Gain AGPAT4 MAP3K4
          nsv1030045 Chr.6:160938043 - 161141223 on Build GRCh38 Gain AGPAT4 MAP3K4
          nsv1026543 Chr.6:160306836 - 161585804 on Build GRCh38 Gain AGPAT4 LPAL2 AGPAT4-IT1 PLG MAP3K4 PARK2 SLC22A3 LPA LOC105378098
          nsv1030852 Chr.6:161056718 - 161168362 on Build GRCh38 Gain AGPAT4 AGPAT4-IT1 MAP3K4

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          More Information


          Set Membership:

          Intragenic Intronic Non-exonic DGV Variation

          Panther Classification:

          Molecular Function -

          non-receptor serine/threonine protein kinase

          Gene Ontology Categories:

          Function(s) Process(es)

          MAPK cascade
          activation of MAPKK activity
          placenta development
          response to UV-C
          regulation of gene expression
          male germ-line sex determination
          positive regulation of telomere maintenance via telomerase
          intracellular signal transduction
          positive regulation of JUN kinase activity
          positive regulation of telomerase activity
          chorionic trophoblast cell differentiation
          positive regulation of p38MAPK cascade
          positive regulation of telomere capping
          MAP kinase kinase kinase activity
          protein binding
          ATP binding
          metal ion binding

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