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          • Home
          • › Search Tool
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          • › Hs06560216_cn
          See other IL6R CNV Assays ›
          Gene Symbol
          IL6R
          Assay Reference Genome
          Location

          Chr.1:154441320 on build GRCh38
          Cytoband
          1q21.3
          Assay ID Hs06560216_cn
          Size
          Availability Made To Order
          Catalog # 4400291
          Price
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          • Genomic Map
          • Assay Details
          • More Information

          Genomic Map

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          Assay Details

          Target Gene Details

          Entrez Gene ID:

          3570

          Gene Name:

          interleukin 6 receptor

          Gene Aliases:

          CD126, IL-6R-1, IL-6RA, IL6Q, IL6RA, IL6RQ, gp80

          Location:

          Chr.1:154405193-154469450 on Build GRCh38

          Assay Gene Location:

          Within Intron 7
          Gene Symbol Transcript Accession Exon Location Assay Transcript Location Protein ID
          IL6R NM_000565.3 NP_000556.1
          NM_181359.2 NP_852004.1
          XM_005245139.1 XP_005245196.1
          XM_005245140.2 XP_005245197.1
          XM_006711298.1 XP_006711361.1
          XM_006711299.3 XP_006711362.1
          XM_017001199.1 XP_016856688.1
          XM_017001200.1 XP_016856689.1
          XM_017001201.1 XP_016856690.1
          AK223582.1 BAD97302.1
          AK293013.1
          AK312730.1
          BC089410.1 AAH89410.1
          BC132684.1
          BC132686.1
          X12830.1 CAA31312.1
          X58298.1 CAA41231.1

          Target Copy Number Variation Details

          DGV Version:

          Release date: 2016-05-15, GRCh GRCh38
          Target
          Variation
          Location CNV
          Subtype
          Genes
          nsv521887 Chr.1:154264094 - 154711630 on Build GRCh38 Gain TDRD10 AQP10 KCNN3 UBE2Q1 CHRNB2 IL6R ATP8B2 LOC101928101 SHE UBAP2L ADAR UBE2Q1-AS1 HAX1

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          More Information


          Set Membership:

          Intragenic Intronic Non-exonic DGV Variation

          Panther Classification:

          Molecular Function -

          transmembrane signal receptor

          Gene Ontology Categories:

          Function(s) Process(es)

          hepatic immune response
          monocyte chemotaxis
          positive regulation of leukocyte chemotaxis
          acute-phase response
          positive regulation of cell proliferation
          cytokine-mediated signaling pathway
          endocrine pancreas development
          positive regulation of chemokine production
          positive regulation of interleukin-6 production
          response to cytokine
          positive regulation of tyrosine phosphorylation of Stat3 protein
          positive regulation of osteoblast differentiation
          positive regulation of smooth muscle cell proliferation
          positive regulation of peptidyl-tyrosine phosphorylation
          defense response to Gram-negative bacterium
          interleukin-6-mediated signaling pathway
          ciliary neurotrophic factor-mediated signaling pathway
          extrinsic apoptotic signaling pathway
          ciliary neurotrophic factor receptor activity
          interleukin-6 receptor activity
          interleukin-6 receptor binding
          protein binding
          enzyme binding
          interleukin-6 binding
          protein homodimerization activity
          ciliary neurotrophic factor binding

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