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          • Home
          • › Search Tool
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          • › Hs07226314_cn
          See other IRF4 CNV Assays ›
          Gene Symbol
          IRF4
          Assay Reference Genome
          Location

          Chr.6:395010 on build GRCh38
          Cytoband
          6p25.3
          Assay ID Hs07226314_cn
          Size
          Availability Made To Order
          Catalog # 4400291
          Price
          Your Price
          Online offer:
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          • Genomic Map
          • Assay Details
          • More Information

          Genomic Map

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          Assay Details

          Target Gene Details

          Entrez Gene ID:

          3662

          Gene Name:

          interferon regulatory factor 4

          Gene Aliases:

          LSIRF, MUM1, NF-EM5, SHEP8

          Location:

          Chr.6:391739-411443 on Build GRCh38

          Assay Gene Location:

          Overlaps Exon 3 - Intron 3
          Gene Symbol Transcript Accession Exon Location Assay Transcript Location Protein ID
          IRF4 NM_001195286.1 NP_001182215.1
          NM_002460.3 NP_002451.2
          NR_046000.2
          XM_006715090.2 XP_006715153.1
          AK310149.1
          BC015752.1 AAH15752.1
          D78261.1 BAA11335.1
          U52682.1 AAC50779.1
          U63738.1 AAB37258.1

          Target Copy Number Variation Details

          DGV Version:

          Release date: 2016-05-15, GRCh GRCh38
          Target
          Variation
          Location CNV
          Subtype
          Genes
          dgv5872n100 Chr.6:231934 - 397937 on Build GRCh38 Gain IRF4 DUSP22
          nsv823390 Chr.6:295899 - 452604 on Build GRCh38 Gain IRF4 DUSP22
          nsv820552 Chr.6:254458 - 396285 on Build GRCh38 Duplication IRF4 DUSP22
          dgv990n67 Chr.6:254941 - 396689 on Build GRCh38 Gain IRF4 DUSP22
          nsv509115 Chr.6:360763 - 416001 on Build GRCh38 Insertion IRF4
          nsv821644 Chr.6:182761 - 411478 on Build GRCh38 Gain IRF4 DUSP22 LOC285766
          nsv1028946 Chr.6:334825 - 404771 on Build GRCh38 Gain IRF4 DUSP22
          nsv830568 Chr.6:232604 - 411249 on Build GRCh38 Gain+Loss IRF4 DUSP22
          esv3607852 Chr.6:381951 - 500339 on Build GRCh38 Loss IRF4 EXOC2
          dgv5869n100 Chr.6:149649 - 395798 on Build GRCh38 Gain IRF4 DUSP22 LOC285766
          nsv600779 Chr.6:383546 - 439985 on Build GRCh38 Loss IRF4
          esv3607835 Chr.6:180946 - 734275 on Build GRCh38 Loss HUS1B IRF4 EXOC2 DUSP22 LOC285766
          dgv5884n100 Chr.6:257341 - 447036 on Build GRCh38 Gain IRF4 DUSP22
          esv2759401 Chr.6:60001 - 775274 on Build GRCh38 Gain+Loss HUS1B IRF4 LINC00266-3 EXOC2 DUSP22 LOC285766

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          More Information


          Additional Information:

          Set Membership:

          Intragenic Non-exonic DGV Variation Validated

          Panther Classification:

          Molecular Function -

          winged helix/forkhead transcription factor

          Gene Ontology Categories:

          Function(s) Process(es)

          transcription from RNA polymerase II promoter
          peptidyl-lysine methylation
          negative regulation of toll-like receptor signaling pathway
          T cell activation
          defense response to protozoan
          myeloid dendritic cell differentiation
          positive regulation of DNA binding
          histone H3 acetylation
          histone H4 acetylation
          positive regulation of interleukin-10 biosynthetic process
          positive regulation of interleukin-2 biosynthetic process
          positive regulation of interleukin-13 biosynthetic process
          positive regulation of interleukin-4 biosynthetic process
          regulation of T-helper cell differentiation
          positive regulation of transcription, DNA-templated
          positive regulation of transcription from RNA polymerase II promoter
          interferon-gamma-mediated signaling pathway
          type I interferon signaling pathway
          T-helper 17 cell lineage commitment
          RNA polymerase II core promoter proximal region sequence-specific DNA binding
          transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding
          transcription factor activity, sequence-specific DNA binding
          protein binding
          transcription factor binding
          protein-lysine N-methyltransferase activity
          sequence-specific DNA binding

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