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          • Home
          • › Search Tool
          • › Search Results
          • › Hs01326481_cn
          See other MCL1 CNV Assays ›
          Gene Symbol
          MCL1
          Assay Reference Genome
          Location

          Chr.1:150579597 on build GRCh38
          Cytoband
          Assay ID Hs01326481_cn
          Size
          Availability Made To Order
          Catalog # 4400291
          Price
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          • Genomic Map
          • Assay Details
          • More Information

          Genomic Map

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          Assay Details

          Target Gene Details

          Entrez Gene ID:

          4170

          Gene Name:

          MCL1 apoptosis regulator, BCL2 family member

          Gene Aliases:

          BCL2L3, EAT, MCL1-ES, MCL1L, MCL1S, Mcl-1, TM, bcl2-L-3, mcl1/EAT

          Location:

          Chr.1:150574558-150579610 on Build GRCh38

          Assay Gene Location:

          Overlaps - Exon 1
          Gene Symbol Transcript Accession Exon Location Assay Transcript Location Protein ID
          MCL1 NM_001197320.2 NP_001184249.1
          NM_021960.5 NP_068779.1
          NM_182763.3 NP_877495.1
          AA453505.1 1 305
          AF118124.1 AAD13299.1
          AK294462.1 BAG57694.1
          AK297217.1 BAG59700.1
          AK300499.1 BAG62213.1
          AK304775.1 BAG65530.1
          AK312508.1 BAG35409.1
          AK316267.1 BAH14638.1
          BC017197.2 AAH17197.1
          BC071897.1 AAH71897.1
          BC107735.1 AAI07736.1
          L08246.1

          Target Copy Number Variation Details

          DGV Version:

          Release date: 2025-12-01, GRCh GRCh38
          Target
          Variation
          Location CNV
          Subtype
          Genes
          nsv1006838 Chr.1:150453465 - 150750307 on Build GRCh38 Gain LOC124904417 ENSA CTSS ADAMTSL4-AS1 FALEC ADAMTSL4-AS2 LOC107985203 MCL1 MIR4257 ECM1 MIR6878 RPRD2 HORMAD1 GOLPH3L ADAMTSL4 TARS2
          nsv6322618 Chr.1:150579001 - 150580100 on Build GRCh38 Deletion LOC107985203 MCL1
          nsv4057833 Chr.1:150439004 - 150716344 on Build GRCh38 Duplication LOC124904417 ENSA ADAMTSL4-AS1 FALEC ADAMTSL4-AS2 LOC107985203 MCL1 MIR4257 ECM1 MIR6878 RPRD2 HORMAD1 GOLPH3L ADAMTSL4 TARS2

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          More Information


          Set Membership:

          Intragenic Non-exonic DGV Variation

          Gene Ontology Categories:

          Function(s) Process(es)

          cell fate determination
          release of cytochrome c from mitochondria
          apoptotic process
          cellular response to DNA damage stimulus
          mitochondrial fusion
          intrinsic apoptotic signaling pathway in response to DNA damage
          negative regulation of autophagy
          cellular homeostasis
          cell differentiation
          response to cytokine
          regulation of apoptotic process
          positive regulation of apoptotic process
          negative regulation of apoptotic process
          positive regulation of neuron apoptotic process
          transmembrane transport
          protein transmembrane transport
          extrinsic apoptotic signaling pathway in absence of ligand
          regulation of intracellular signal transduction
          positive regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway
          negative regulation of anoikis
          regulation of apoptotic signaling pathway
          negative regulation of extrinsic apoptotic signaling pathway in absence of ligand
          protein binding
          protein transmembrane transporter activity
          channel activity
          protein heterodimerization activity
          BH domain binding
          BH3 domain binding

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