Assay Details

Gene Symbol: IL2
Interrogated Sequence		Translated Protein	Exon Boundary	Assay Location	IMAGE Clone ID	Amplicon Length
RefSeq	NM_000586.3	NP_000577.2	2 - 3	267		94
RefSeq	XM_017008177.1	XP_016863666.1	2 - 3	233		94
GenBank mRNA	A14844.1	-	2 - 3	222		94
	AB451325.1	-	2 - 3	212		94
	AB451454.1	-	2 - 3	212		94
	AF228636.1	-	2 - 3	224		94
	AY523040.1	-	2 - 3	152		94
	BC066254.1	-	2 - 3	230	6971690	94
	BC066255.1	-	2 - 3	230	6971691	94
	BC066256.1	-	2 - 3	230	6971693	94
	BC066257.1	-	2 - 3	230	6971694	94
	BC070338.1	-	2 - 3	259	30418817	94
	DQ231169.1	-	2 - 3	152		94
	DQ861285.1	-	2 - 3	214		94
	S77834.1	-	2 - 3	259		94
	S77835.1	-	2 - 3	201		94
	S82692.1	-	2 - 3	506		94
	U25676.1	-	2 - 3	268		94
	V00564.1	-	2 - 3	259		94
	X01586.1	-	2 - 3	319		94

More Information

Updated Mapping Information

This assay targets the same location as Clariom D transcript cluster(s) TC0400011754.hg.1
This assay targets the same location as HTA transcript cluster(s) TC04001520.hg.1

Set Membership:

Ambion siRNA available

Amplicon length between 86 and 100

3' Most

Immune Tolerance Network

Mammalian Gene Collection

Recommended Assay

Homo sapiens

Human Chemokine Panel

Human Immune Response

Human NFkB Pathway

Human Hematopoeisis

Human IL-2 Pathway

Human Signal Transduction Pathways

Human Growth Factors

Human Cytokine Network

Human IL-2 Gene Expression in Activated and Quiescent T-Cell

HUMAN 14-3-3 INDUCED INTRACELLULAR SIGNALING

HUMAN CREB PATHWAY

HUMAN ENOS SIGNALING

HUMAN BREAST CANCER REGULATION BY STATHMIN1

HUMAN P53 MEDIATED APOPTOSIS

HUMAN IL-6 PATHWAY

HUMAN PATHOGENESIS OF RHEUMATOID ARTHRITIS

HUMAN CELLULAR APOPTOSIS PATHWAY

Inventoried

Human_Immune

Human_Nfkb

Human_Cytokine_Network

Human_IL-2_Gene_Expression_in_Activated_and_Quiescent_T-Cells

Human_Growth_Factors

Human_Chemokine

Human_Hematopoisis

Human_Signal_Transduction_Pathways

Human_IL-2_Pathway

Human_Pathogenesis_of_Rheumatoid_Arthritis

Human_IL-6_Pathway

Human_14-3-3_Induced_Intracellular_Signaling

Human_eNOS_Signaling

Human_CREB_Pathway

Human_p53_Mediated_Apoptosis

Human_Cellular_Apoptosis_Pathway

Human_Breast_Cancer_Regulation_by_Stathmin1

Probe spans exons

Matching Ambion siRNAs:

Click here to find siRNAs for Gene IL2

Gene Ontology Categories:

Function(s) Process(es)

MicroArray Probes:

Affymetrix

Array Name	Probe IDs	Targets	Target Type
Affymetrix Human Transcriptome Array 2.0	TC0400011754.hg.1	ENST00000226730.4	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC0400011754.hg.1	ENST00000226730.4	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC0400011754.hg.1	ENST00000226730.4	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC0400011754.hg.1	ENST00000226730.4	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC0400011754.hg.1	ENST00000226730.4	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC0400011754.hg.1	ENST00000226730.4	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC0400011754.hg.1	ENST00000226730.4	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC0400011754.hg.1	ENST00000226730.4	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC0400011754.hg.1	ENST00000226730.4	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC0400011754.hg.1	ENST00000477645.1	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC0400011754.hg.1	ENST00000477645.1	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC0400011754.hg.1	ENST00000477645.1	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC0400011754.hg.1	ENST00000477645.1	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC0400011754.hg.1	ENST00000477645.1	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC0400011754.hg.1	ENST00000477645.1	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC0400011754.hg.1	NM_000586.3	Refseq
Affymetrix Human Transcriptome Array 2.0	TC0400011754.hg.1	NM_000586.3	Refseq
Affymetrix Human Transcriptome Array 2.0	TC0400011754.hg.1	NM_000586.3	Refseq
Affymetrix Human Transcriptome Array 2.0	TC0400011754.hg.1	NM_000586.3	Refseq
Affymetrix Human Transcriptome Array 2.0	TC0400011754.hg.1	NM_000586.3	Refseq
Affymetrix Human Transcriptome Array 2.0	TC0400011754.hg.1	NM_000586.3	Refseq
Affymetrix Human Transcriptome Array 2.0	TC0400011754.hg.1	NM_000586.3	Refseq
Affymetrix Human Transcriptome Array 2.0	TC0400011754.hg.1	NM_000586.3	Refseq
Affymetrix Human Transcriptome Array 2.0	PSR04021599.hg.1	TC04001520.hg.1	HTA TC
Affymetrix Human Transcriptome Array 2.0	PSR04021599.hg.1	ENST00000226730.4	Ensembl
Affymetrix Human Transcriptome Array 2.0	PSR04021599.hg.1	NM_000586.3	Refseq
Affymetrix Human Clariom D Assay	PSR0400180911.hg.1	ENST00000226730.4	Ensembl
Affymetrix Human Clariom D Assay	PSR0400180911.hg.1	ENST00000477645.1	Ensembl
Affymetrix Human Clariom D Assay	PSR0400180911.hg.1	NM_000586.3	Refseq
Affymetrix Human Clariom D Assay	PSR0400180911.hg.1	ENST00000226730.4	Ensembl
Affymetrix Human Clariom D Assay	PSR0400180911.hg.1	ENST00000477645.1	Ensembl
Affymetrix Human Clariom D Assay	PSR0400180911.hg.1	NM_000586.3	Refseq
Affymetrix Human Clariom D Assay	PSR0400180911.hg.1	TC0400011754.hg.1	Clariom D TC
Affymetrix Human Clariom D Assay	TC0400011754.hg.1	ENST00000226730.4	Ensembl
Affymetrix Human Clariom D Assay	TC0400011754.hg.1	ENST00000226730.4	Ensembl
Affymetrix Human Clariom D Assay	TC0400011754.hg.1	ENST00000226730.4	Ensembl
Affymetrix Human Clariom D Assay	TC0400011754.hg.1	ENST00000226730.4	Ensembl
Affymetrix Human Clariom D Assay	TC0400011754.hg.1	ENST00000226730.4	Ensembl
Affymetrix Human Clariom D Assay	TC0400011754.hg.1	ENST00000226730.4	Ensembl
Affymetrix Human Clariom D Assay	TC0400011754.hg.1	ENST00000226730.4	Ensembl
Affymetrix Human Clariom D Assay	TC0400011754.hg.1	ENST00000226730.4	Ensembl
Affymetrix Human Clariom D Assay	TC0400011754.hg.1	ENST00000226730.4	Ensembl
Affymetrix Human Clariom D Assay	TC0400011754.hg.1	ENST00000477645.1	Ensembl
Affymetrix Human Clariom D Assay	TC0400011754.hg.1	ENST00000477645.1	Ensembl
Affymetrix Human Clariom D Assay	TC0400011754.hg.1	ENST00000477645.1	Ensembl
Affymetrix Human Clariom D Assay	TC0400011754.hg.1	ENST00000477645.1	Ensembl
Affymetrix Human Clariom D Assay	TC0400011754.hg.1	ENST00000477645.1	Ensembl
Affymetrix Human Clariom D Assay	TC0400011754.hg.1	ENST00000477645.1	Ensembl
Affymetrix Human Clariom D Assay	TC0400011754.hg.1	NM_000586.3	Refseq
Affymetrix Human Clariom D Assay	TC0400011754.hg.1	NM_000586.3	Refseq
Affymetrix Human Clariom D Assay	TC0400011754.hg.1	NM_000586.3	Refseq
Affymetrix Human Clariom D Assay	TC0400011754.hg.1	NM_000586.3	Refseq
Affymetrix Human Clariom D Assay	TC0400011754.hg.1	NM_000586.3	Refseq
Affymetrix Human Clariom D Assay	TC0400011754.hg.1	NM_000586.3	Refseq
Affymetrix Human Clariom D Assay	TC0400011754.hg.1	NM_000586.3	Refseq
Affymetrix Human Clariom D Assay	TC0400011754.hg.1	NM_000586.3	Refseq

Citations (18)

Intragraft expression of the IL-10 gene is up-regulated in renal protocol biopsies with early interstitial fibrosis, tubular atrophy, and subclinical rejection.

Authors: Hueso M, Navarro E, Moreso F, O'Valle F, Perez-Riba M, Del Moral RG, Grinyo JM, Seron D
Journal: Am J Pathol - Page No 1696 (Thu Apr 01 00:00:00 EDT 2010)
Volume (Year): 176 (2010)
Product Usage: -

Hypercytokinaemia accompanies HIV-tuberculosis immune reconstitution inflammatory syndrome.

Authors: Tadokera R, Meintjes G, Skolimowska KH, Wilkinson KA, Matthews K, Seldon R, Chegou NN, Maartens G, Rangaka MX, Rebe K, Walzl G, Wilkinson RJ
Journal: Eur Respir J - Page No (Fri Sep 03 00:00:00 EDT 2010)
Volume (Year): (2010)
Product Usage: -

Altered expression of T cell immunoglobulin-mucin (TIM) molecules in bronchoalveolar lavage CD4+ T cells in sarcoidosis.

Authors: Idali F, Wahlstrom J, Dahlberg B, Khademi M, Olsson T, Eklund A, Grunewald J
Journal: Respir Res - Page No 42 (Thu Jan 01 00:00:00 EST 2009)
Volume (Year): 10 (2009)
Product Usage: -

Sotrastaurin and cyclosporine drug interaction study in healthy subjects.

Authors: Kovarik JM, Stitah S, Slade A, Vitaliti A, Straube F, Grenet O, Winter S, Sfikas N, Seiberling M
Journal: Biopharm Drug Dispos - Page No 331 (Thu Jul 01 00:00:00 EDT 2010)
Volume (Year): 31 (2010)
Product Usage: -

Inflammatory and microRNA Gene Expression as Prognostic Classifiers of Barrett's Associated Esophageal Adenocarcinoma.

Authors: Nguyen GH, Schetter AJ, Chou DB, Bowman ED, Zhao R, Hawkes JE, Mathe E, Kumamoto K, Zhao Y, Budhu A, Hagiwara N, Wang XW, Miyashita M, Casson AG, Harris CC
Journal: Clin Cancer Res - Page No (Mon Oct 25 00:00:00 EDT 2010)
Volume (Year): (2010)
Product Usage: -

The effect of the JAK inhibitor CP-690,550 on peripheral immune parameters in stable kidney allograft patients.

Authors: van Gurp EA, Schoordijk-Verschoor W, Klepper M, Korevaar SS, Chan G, Weimar W, Baan CC
Journal: Transplantation - Page No 79 (Thu Jan 15 00:00:00 EST 2009)
Volume (Year): 87 (2009)
Product Usage: -

Requirement for O-linked N-acetylglucosaminyltransferase in lymphocytes activation.

Authors: Golks A, Tran TT, Goetschy JF, Guerini D
Journal: Embo J - Page No 4368 (Wed Oct 17 00:00:00 EDT 2007)
Volume (Year): 26 (2007)
Product Usage: -

Induction of Foxp3+ regulatory T cells with histone deacetylase inhibitors.

Authors: Lucas JL, Mirshahpanah P, Haas-Stapleton E, Asadullah K, Zollner TM, Numerof RP
Journal: Cell Immunol - Page No 97 (Thu Jan 01 00:00:00 EST 2009)
Volume (Year): 257 (2009)
Product Usage: -

Differential expression patterns of cytokines in complex regional pain syndrome.

Authors: Uceyler N, Eberle T, Rolke R, Birklein F, Sommer C
Journal: Pain - Page No 195 (Thu Nov 01 00:00:00 EDT 2007)
Volume (Year): 132 (2007)
Product Usage: -

Intragraft FOXP3 mRNA expression reflects antidonor immune reactivity in cardiac allograft patients.

Authors: Dijke IE, Velthuis JH, Caliskan K, Korevaar SS, Maat AP, Zondervan PE, Balk AH, Weimar W, Baan CC
Journal: Transplantation - Page No 1477 (Fri Jun 15 00:00:00 EDT 2007)
Volume (Year): 83 (2007)
Product Usage: -

Soluble Ig-like transcript 3 inhibits tumor allograft rejection in humanized SCID mice and T cell responses in cancer patients.

Authors: Suciu-Foca N, Feirt N, Zhang QY, Vlad G, Liu Z, Lin H, Chang CC, Ho EK, Colovai AI, Kaufman H, D'Agati VD, Thaker HM, Remotti H, Galluzzo S, Cinti P, Rabitti C, Allendorf J, Chabot J, Caricato M, Coppola R, Berloco P, Cortesini R
Journal: J Immunol - Page No 7432 (Fri Jun 01 00:00:00 EDT 2007)
Volume (Year): 178 (2007)
Product Usage: -

Mycolactone suppresses T cell responsiveness by altering both early signaling and posttranslational events.

Authors: Boulkroun S, Guenin-Mace L, Thoulouze MI, Monot M, Merckx A, Langsley G, Bismuth G, Di Bartolo V, Demangel C
Journal: J Immunol - Page No 1436 (Mon Feb 01 00:00:00 EST 2010)
Volume (Year): 184 (2010)
Product Usage: -

End-stage renal failure and regulatory activities of CD4+CD25bright+FoxP3+ T-cells.

Authors: Hendrikx TK, van Gurp EA, Mol WM, Schoordijk W, Sewgobind VD, Ijzermans JN, Weimar W, Baan CC
Journal: Nephrol Dial Transplant - Page No 1969 (Mon Jun 01 00:00:00 EDT 2009)
Volume (Year): 24 (2009)
Product Usage: -

Essential role of IL-21 in B cell activation, expansion, and plasma cell generation during CD4+ T cell-B cell collaboration.

Authors: Kuchen S, Robbins R, Sims GP, Sheng C, Phillips TM, Lipsky PE, Ettinger R
Journal: J Immunol - Page No 5886 (Thu Nov 01 00:00:00 EDT 2007)
Volume (Year): 179 (2007)
Product Usage: -

Interplay between human adipocytes and T lymphocytes in obesity: CCL20 as an adipochemokine and T lymphocytes as lipogenic modulators.

Authors: Duffaut C, Zakaroff-Girard A, Bourlier V, Decaunes P, Maumus M, Chiotasso P, Sengenes C, Lafontan M, Galitzky J, Bouloumie A
Journal: Arterioscler Thromb Vasc Biol - Page No 1608 (Thu Oct 01 00:00:00 EDT 2009)
Volume (Year): 29 (2009)
Product Usage: -

Characterization of rabbit antithymocyte globulins-induced CD25+ regulatory T cells from cells of patients with end-stage renal disease.

Authors: Sewgobind VD, van der Laan LJ, Kho MM, Kraaijeveld R, Korevaar SS, van Dam T, Ijzermans JN, Weimar W, Baan CC
Journal: Transplantation - Page No 655 (Sat Mar 27 00:00:00 EDT 2010)
Volume (Year): 89 (2010)
Product Usage: -

ITPKC functional polymorphism associated with Kawasaki disease susceptibility and formation of coronary artery aneurysms.

Authors: Onouchi Y, Gunji T, Burns JC, Shimizu C, Newburger JW, Yashiro M, Nakamura Y, Yanagawa H, Wakui K, Fukushima Y, Kishi F, Hamamoto K, Terai M, Sato Y, Ouchi K, Saji T, Nariai A, Kaburagi Y, Yoshikawa T, Suzuki K, Tanaka T, Nagai T, Cho H, Fujino A, Sekine A, Nakamichi R, Tsunoda T, Kawasaki T, Nakamura Y, Hata A
Journal: Nat Genet - Page No 35 (Tue Jan 01 00:00:00 EST 2008)
Volume (Year): 40 (2008)
Product Usage: -

Local and systemic cytokine and chemokine responses after parenteral influenza vaccination.

Authors: Eriksson JC, Cox RJ, Szyszko E, Davidsson A, Brokstad KA
Journal: Influenza Other Respi Viruses - Page No 139 (Sun Jul 01 00:00:00 EDT 2007)
Volume (Year): 1 (2007)
Product Usage: -

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Catalog #	4331182
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System Message

Genomic Map