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          System Message

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          LOADING ...
          Gene:
          ATM
          Transcript:
          NM_000051.3
          Assay Name:
          Mutation genome location:
          chr.11 108304405-108304937 on build GRCh38
          Assay ID Hs00111959_CE

          Purification
          Size
          Availability Made To Order
          Catalog # A15629
          Price
          Your Price
          Online offer:
          Check your price ›
          • Genomic Map
          • Assay Details
          • More Information

          Genomic Map

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          Assay Details


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          More Information


          Set Membership:

          Between 400-700 bp

          Panther Classification:

          Molecular Function -

          non-receptor serine/threonine protein kinase

          Gene Ontology Categories:

          Function(s) Process(es)

          double-strand break repair via homologous recombination
          DNA double-strand break processing
          DNA synthesis involved in DNA repair
          strand displacement
          response to hypoxia
          somitogenesis
          pre-B cell allelic exclusion
          DNA replication
          DNA repair
          double-strand break repair via nonhomologous end joining
          protein phosphorylation
          cellular response to DNA damage stimulus
          DNA damage induced protein phosphorylation
          DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest
          telomere maintenance via telomerase
          cell cycle arrest
          mitotic spindle assembly checkpoint
          reciprocal meiotic recombination
          signal transduction
          brain development
          heart development
          determination of adult lifespan
          intrinsic apoptotic signaling pathway in response to DNA damage
          response to ionizing radiation
          regulation of autophagy
          histone phosphorylation
          peptidyl-serine phosphorylation
          negative regulation of B cell proliferation
          positive regulation of telomere maintenance via telomerase
          positive regulation of histone phosphorylation
          V(D)J recombination
          phosphatidylinositol-3-phosphate biosynthetic process
          peptidyl-serine autophosphorylation
          lipoprotein catabolic process
          regulation of apoptotic process
          positive regulation of apoptotic process
          positive regulation of DNA damage response, signal transduction by p53 class mediator
          positive regulation of neuron apoptotic process
          meiotic telomere clustering
          protein autophosphorylation
          oocyte development
          neuron apoptotic process
          regulation of telomerase activity
          histone mRNA catabolic process
          cellular response to gamma radiation
          cellular response to X-ray
          cellular response to nitrosative stress
          signal transduction involved in mitotic G2 DNA damage checkpoint
          replicative senescence
          establishment of RNA localization to telomere
          establishment of macromolecular complex localization to telomere
          regulation of cellular response to heat
          regulation of signal transduction by p53 class mediator
          negative regulation of TORC1 signaling
          negative regulation of telomere capping
          positive regulation of telomere maintenance via telomere lengthening
          positive regulation of telomerase catalytic core complex assembly
          DNA binding
          protein serine/threonine kinase activity
          DNA-dependent protein kinase activity
          protein binding
          ATP binding
          1-phosphatidylinositol-3-kinase activity
          protein complex binding
          protein dimerization activity
          protein N-terminus binding

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          Host server : magellan-search-blue-67655d8755-zsnhf:80/100.66.75.14:80.
          git-commit: dddaa802cd395f65bf1581942d0e97a089c38f41
          git-url: https://github.com/thermofisher/magellan-search
          git-branch: release/2.46.0-Offline