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          System Message

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          LOADING ...
          Gene:
          ZC3H12A
          Transcript:
          Assay Name:
          Mutation genome location:
          chr.1 37482654-37483158 on build GRCh38
          Assay ID Hs00170728_CE

          Purification
          Size
          Availability Made To Order
          Catalog # A15629
          Price
          Your Price
          Online offer:
          Check your price ›
          • Genomic Map
          • Assay Details
          • More Information

          Genomic Map

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          Assay Details


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          More Information


          Set Membership:

          Between 400-700 bp

          Panther Classification:

          Molecular Function -

          endoribonuclease

          Gene Ontology Categories:

          Function(s) Process(es)

          nuclear-transcribed mRNA catabolic process, endonucleolytic cleavage-dependent decay
          angiogenesis
          negative regulation of protein phosphorylation
          positive regulation of defense response to virus by host
          transcription, DNA-templated
          apoptotic process
          inflammatory response
          cellular response to DNA damage stimulus
          nervous system development
          regulation of gene expression
          positive regulation of autophagy
          positive regulation of endothelial cell migration
          positive regulation of gene expression
          negative regulation of gene expression
          negative regulation of muscle cell apoptotic process
          positive regulation of lipid storage
          positive regulation of cell death
          protein deubiquitination
          cell differentiation
          negative regulation of NF-kappaB transcription factor activity
          negative regulation of interleukin-6 production
          negative regulation of tumor necrosis factor production
          cellular response to oxidative stress
          cellular response to glucose starvation
          positive regulation of protein import into nucleus
          negative regulation of NF-kappaB import into nucleus
          negative regulation of macrophage activation
          negative regulation of I-kappaB kinase/NF-kappaB signaling
          negative regulation by host of viral genome replication
          negative regulation of nitric oxide biosynthetic process
          positive regulation of fat cell differentiation
          positive regulation of angiogenesis
          positive regulation of transcription from RNA polymerase II promoter
          negative regulation of interleukin-1 beta secretion
          protein oligomerization
          defense response to virus
          negative regulation of cardiac muscle contraction
          positive regulation of mRNA catabolic process
          3'-UTR-mediated mRNA destabilization
          cellular response to lipopolysaccharide
          cellular response to interleukin-1
          cellular response to tumor necrosis factor
          RNA phosphodiester bond hydrolysis
          RNA phosphodiester bond hydrolysis, endonucleolytic
          RNA phosphodiester bond hydrolysis, exonucleolytic
          cellular response to virus
          negative regulation of cytokine production involved in inflammatory response
          positive regulation of execution phase of apoptosis
          negative regulation of interleukin-6 secretion
          positive regulation of p38MAPK cascade
          negative regulation of interferon-gamma secretion
          positive regulation of protein deubiquitination
          negative regulation of production of miRNAs involved in gene silencing by miRNA
          cellular response to sodium arsenite
          negative regulation of tumor necrosis factor secretion
          cellular response to phorbol 13-acetate 12-myristate
          cellular response to ionomycin
          cellular response to chemokine
          positive regulation of reactive oxygen species metabolic process
          positive regulation of miRNA catabolic process
          DNA binding
          chromatin binding
          RNA binding
          mRNA binding
          mRNA 3'-UTR binding
          endoribonuclease activity
          exoribonuclease activity
          ribonuclease activity
          thiol-dependent ubiquitin-specific protease activity
          protein binding
          miRNA binding
          RNA stem-loop binding
          mRNA 3'-UTR AU-rich region binding
          ribosome binding
          metal ion binding

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          Host server : magellan-search-green-b49b87d85-5cvsx:80/100.66.79.163:80.
          git-commit: 5b8c860b7cdb41e9cfe07630520f6b51e109d38e
          git-url: https://github.com/thermofisher/magellan-search
          git-branch: release/2.47.0-Offline