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          System Message

          OKCancel
          LOADING ...
          Gene:
          SMAD2
          Transcript:
          Assay Name:
          Mutation genome location:
          chr.18 47840508-47841055 on build GRCh38
          Assay ID Hs00351007_CE

          Purification
          Size
          Availability Made To Order
          Catalog # A15629
          Price
          Your Price
          Online offer:
          Check your price ›
          • Genomic Map
          • Assay Details
          • More Information

          Genomic Map

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          Assay Details


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          More Information


          Set Membership:

          Between 400-700 bp

          Panther Classification:

          Molecular Function -

          DNA-binding transcription factor gene-specific transcriptional regulator

          Gene Ontology Categories:

          Function(s) Process(es)

          negative regulation of transcription from RNA polymerase II promoter
          ureteric bud development
          in utero embryonic development
          endoderm formation
          mesoderm formation
          transcription from RNA polymerase II promoter
          transforming growth factor beta receptor signaling pathway
          common-partner SMAD protein phosphorylation
          SMAD protein complex assembly
          zygotic specification of dorsal/ventral axis
          gastrulation
          negative regulation of cell proliferation
          response to glucose
          post-embryonic development
          anterior/posterior pattern specification
          positive regulation of epithelial to mesenchymal transition
          regulation of transforming growth factor beta receptor signaling pathway
          signal transduction involved in regulation of gene expression
          insulin secretion
          lung development
          negative regulation of transforming growth factor beta receptor signaling pathway
          positive regulation of BMP signaling pathway
          pancreas development
          primary miRNA processing
          activin receptor signaling pathway
          somatic stem cell population maintenance
          organ growth
          intracellular signal transduction
          nodal signaling pathway
          cell fate commitment
          negative regulation of transcription, DNA-templated
          positive regulation of transcription, DNA-templated
          positive regulation of transcription from RNA polymerase II promoter
          paraxial mesoderm morphogenesis
          embryonic foregut morphogenesis
          embryonic cranial skeleton morphogenesis
          regulation of binding
          palate development
          pericardium development
          SMAD protein signal transduction
          response to cholesterol
          positive regulation of nodal signaling pathway involved in determination of lateral mesoderm left/right asymmetry
          RNA polymerase II core promoter proximal region sequence-specific DNA binding
          transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding
          DNA binding
          chromatin binding
          double-stranded DNA binding
          transcription factor activity, sequence-specific DNA binding
          transforming growth factor beta receptor binding
          protein binding
          transcription factor binding
          phosphatase binding
          transforming growth factor beta receptor, pathway-specific cytoplasmic mediator activity
          ubiquitin protein ligase binding
          activating transcription factor binding
          type I transforming growth factor beta receptor binding
          enhancer binding
          protein homodimerization activity
          SMAD binding
          metal ion binding
          protein heterodimerization activity
          co-SMAD binding
          I-SMAD binding
          R-SMAD binding

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          Host server : magellan-search-green-b49b87d85-5cvsx:80/100.66.79.163:80.
          git-commit: 5b8c860b7cdb41e9cfe07630520f6b51e109d38e
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