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          System Message

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          LOADING ...
          See other SMO SIRNA Assays ›
          Gene Symbol:
          SMO
          Gene Name:
          smoothened, frizzled class receptor
          Gene Aliases:
          FZD11, Gx, SMOH
          Chromosome Location:
          Chr.7: 129188872 - 129213548 on Build GRCh38
          UniGene ID:
          Hs.437846
          Species:
          Human
          Species Specific ID (Flybase ID):
          -
          siRNA ID 1885

          Purification
          Size
          Availability Inventoried
          Catalog # AM16708
          Price 286.00
          Your Price
          Online offer: 277.65
          277.65
          Check your price ›
          • Genomic Map
          • siRNA Details
          • More Information

          Genomic Map

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          siRNA Details

          Gene Symbol: SMO
          Interrogated Sequence Translated Protein Targeted Exon(s) siRNA Location IMAGE Clone ID
          RefSeq NM_005631.4 NP_005622.1 3 972
          XM_011516522.2 XP_011514824.1 4 538
          GenBank mRNA AF071494.1 - 3 692
          AF120103.1 - 3 750
          BC009989.2 - 3 972 4127774
          U84401.1 - 3 692

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          More Information


          Other Species Targeted

          This siRNA also targets the following transcripts in Mouse: NM_176996, BC096028, BC048091, CN665198, FJ883552.

          Set Membership:

          G-protein coupled receptor

          Panther Classification:

          Molecular Function -

          transmembrane signal receptor

          Gene Ontology Categories:

          Function(s) Process(es)

          negative regulation of transcription from RNA polymerase II promoter
          vasculogenesis
          osteoblast differentiation
          in utero embryonic development
          cell fate specification
          neural crest cell migration
          heart looping
          positive regulation of neuroblast proliferation
          positive regulation of mesenchymal cell proliferation
          determination of left/right asymmetry in lateral mesoderm
          type B pancreatic cell development
          G-protein coupled receptor signaling pathway
          smoothened signaling pathway
          positive regulation of hh target transcription factor activity
          ventral midline determination
          midgut development
          anterior/posterior pattern specification
          positive regulation of gene expression
          negative regulation of gene expression
          dentate gyrus development
          cerebellar cortex morphogenesis
          thalamus development
          dorsal/ventral neural tube patterning
          smoothened signaling pathway involved in ventral spinal cord patterning
          smoothened signaling pathway involved in regulation of cerebellar granule cell precursor cell proliferation
          central nervous system neuron differentiation
          cerebral cortex development
          negative regulation of epithelial cell differentiation
          hair follicle morphogenesis
          protein localization to nucleus
          multicellular organism growth
          non-canonical Wnt signaling pathway
          positive regulation of multicellular organism growth
          positive regulation of protein import into nucleus
          odontogenesis of dentin-containing tooth
          negative regulation of apoptotic process
          negative regulation of DNA binding
          positive regulation of smoothened signaling pathway
          positive regulation of transcription from RNA polymerase II promoter
          positive regulation of organ growth
          astrocyte activation
          skeletal muscle fiber development
          forebrain morphogenesis
          homeostasis of number of cells within a tissue
          positive regulation of epithelial cell proliferation
          protein stabilization
          myoblast migration
          negative regulation of hair follicle development
          canonical Wnt signaling pathway
          detection of cell density by contact stimulus involved in contact inhibition
          atrial septum morphogenesis
          mammary gland epithelial cell differentiation
          epithelial-mesenchymal cell signaling
          somite development
          pancreas morphogenesis
          left/right axis specification
          cellular response to cholesterol
          renal system development
          mesenchymal to epithelial transition involved in metanephric renal vesicle formation
          positive regulation of branching involved in ureteric bud morphogenesis
          regulation of stem cell population maintenance
          regulation of heart morphogenesis
          G-protein coupled receptor activity
          patched binding
          protein binding
          drug binding
          Wnt-protein binding
          Wnt-activated receptor activity

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