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          System Message

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          LOADING ...
          See other TIRAP SIRNA Assays ›
          Gene Symbol:
          TIRAP
          Gene Name:
          TIR domain containing adaptor protein
          Gene Aliases:
          BACTS1, Mal, MyD88-2, wyatt
          Chromosome Location:
          Chr.11: 126281268 - 126294933 on Build GRCh38
          UniGene ID:
          Hs.537126
          Species:
          Human
          Species Specific ID (Flybase ID):
          -
          siRNA ID 44751

          Purification
          Size
          Availability Inventoried
          Catalog # AM16708
          Price
          Your Price
          Online offer:
          Check your price ›
          • Genomic Map
          • siRNA Details
          • More Information

          Genomic Map

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          siRNA Details

          Gene Symbol: TIRAP
          Interrogated Sequence Translated Protein Targeted Exon(s) siRNA Location IMAGE Clone ID
          RefSeq NM_001039661.1 NP_001034750.1 5 1069
          NM_001318776.1 NP_001305705.1 4 916
          NM_001318777.1 NP_001305706.1 4 916
          NM_148910.2 NP_683708.1 5 1085
          XM_005271399.3 XP_005271456.2 3 814
          XM_011542576.2 XP_011540878.1 3 814
          XM_017017161.1 XP_016872650.1 2 2437
          XM_017017162.1 XP_016872651.1 5 1106
          GenBank mRNA AB446477.1 - 2 633
          AF378129.1 - 5 1066
          AF406652.1 - 2 633
          AF410783.1 - 5 1062
          AK124298.1 - 4 916
          AK313147.1 - 4 909
          AY576785.1 - 2 672
          AY576786.1 - 2 672
          AY576787.1 - 2 672
          BC032474.1 - 5 1038 5216171

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          More Information


          Gene Ontology Categories:

          Function(s) Process(es)

          MyD88-dependent toll-like receptor signaling pathway
          inflammatory response
          cell surface receptor signaling pathway
          activation of NF-kappaB-inducing kinase activity
          myeloid cell differentiation
          positive regulation of B cell proliferation
          response to lipopolysaccharide
          regulation of interferon-beta production
          positive regulation of interleukin-12 production
          positive regulation of interleukin-15 production
          positive regulation of interleukin-8 production
          positive regulation of tumor necrosis factor production
          positive regulation of toll-like receptor 2 signaling pathway
          positive regulation of toll-like receptor 3 signaling pathway
          toll-like receptor 4 signaling pathway
          positive regulation of toll-like receptor 4 signaling pathway
          TIRAP-dependent toll-like receptor 4 signaling pathway
          positive regulation of I-kappaB kinase/NF-kappaB signaling
          negative regulation of growth of symbiont in host
          innate immune response
          regulation of innate immune response
          positive regulation of interleukin-6 biosynthetic process
          positive regulation of JNK cascade
          defense response to Gram-positive bacterium
          positive regulation of NF-kappaB transcription factor activity
          positive regulation of ERK1 and ERK2 cascade
          3'-UTR-mediated mRNA stabilization
          cellular response to bacterial lipopeptide
          cellular response to lipoteichoic acid
          positive regulation of neutrophil chemotaxis
          positive regulation of protein homodimerization activity
          positive regulation of chemokine (C-X-C motif) ligand 1 production
          positive regulation of chemokine (C-X-C motif) ligand 2 production
          protein kinase C binding
          protein binding
          phosphatidylinositol-4,5-bisphosphate binding
          protein binding, bridging
          Toll-like receptor 4 binding
          Toll-like receptor 2 binding
          protein homodimerization activity
          protein heterodimerization activity

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