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          System Message

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          LOADING ...
          See other ARRB2 SIRNA Assays ›
          Gene Symbol:
          ARRB2
          Gene Name:
          arrestin beta 2
          Gene Aliases:
          ARB2, ARR2, BARR2
          Chromosome Location:
          Chr.17: 4710494 - 4721500 on Build GRCh38
          UniGene ID:
          Hs.435811
          Species:
          Human
          Species Specific ID (Flybase ID):
          -
          siRNA ID HSS180982
          Size 20 nmol
          Availability Made To Order
          Catalog # 1299001
          Price
          Your Price
          Online offer:
          Check your price ›
          • Genomic Map
          • siRNA Details
          • More Information

          Genomic Map

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          siRNA Details

          Gene Symbol: ARRB2
          Interrogated Sequence Translated Protein Targeted Exon(s) siRNA Location IMAGE Clone ID
          RefSeq NM_001257328.1 NP_001244257.1 1, 2 251
          NM_001257329.1 NP_001244258.1 1, 2 251
          NM_001257330.1 NP_001244259.1 1, 2 251
          NM_001257331.1 NP_001244260.1 1, 2 251
          NM_004313.3 NP_004304.1 1, 2 251
          NM_199004.1 NP_945355.1 1, 2 251
          GenBank mRNA AF106941.1 - 1, 2 76
          AK097542.1 - 1, 2 111
          AK290951.1 - 1, 2 52
          BC007427.2 - 1, 2 85 3028154
          BC039066.1 - 14
          BC067368.1 - 1, 2 79 5748319
          BC095450.1 - 1, 2 49
          BG723452.1 - 1, 2 261
          CR450310.1 - 1, 2 23
          DQ664180.1 - 1, 2 23
          EU883572.1 - 1, 2 23
          Z11501.1 - 1, 2 23

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          More Information


          Other Species Targeted

          This siRNA also targets the following transcripts in Rat: NM_012911, BC087578, M91590.
          This siRNA also targets the following transcripts in Mouse: NM_145429, NM_001271360, NM_001271358, NM_001271359, AK150389, and others.

          Panther Classification:

          Molecular Function -

          scaffold/adaptor protein

          Gene Ontology Categories:

          Function(s) Process(es)

          G-protein coupled receptor internalization
          desensitization of G-protein coupled receptor protein signaling pathway by arrestin
          positive regulation of receptor internalization
          transcription from RNA polymerase II promoter
          transforming growth factor beta receptor signaling pathway
          dopamine receptor signaling pathway
          brain development
          adult walking behavior
          protein transport
          protein ubiquitination
          platelet activation
          negative regulation of protein ubiquitination
          positive regulation of protein ubiquitination
          receptor internalization
          negative regulation of NF-kappaB transcription factor activity
          positive regulation of synaptic transmission, dopaminergic
          negative regulation of interleukin-1 beta production
          negative regulation of interleukin-12 production
          negative regulation of interleukin-6 production
          negative regulation of tumor necrosis factor production
          positive regulation of peptidyl-serine phosphorylation
          negative regulation of toll-like receptor signaling pathway
          negative regulation of GTPase activity
          negative regulation of smooth muscle cell apoptotic process
          follicle-stimulating hormone signaling pathway
          negative regulation of cysteine-type endopeptidase activity involved in apoptotic process
          proteasome-mediated ubiquitin-dependent protein catabolic process
          negative regulation of natural killer cell mediated cytotoxicity
          positive regulation of peptidyl-tyrosine phosphorylation
          detection of temperature stimulus involved in sensory perception of pain
          positive regulation of protein kinase B signaling
          negative regulation of protein kinase B signaling
          positive regulation of calcium ion transport
          Wnt signaling pathway, planar cell polarity pathway
          cell chemotaxis
          regulation of androgen receptor signaling pathway
          positive regulation of ERK1 and ERK2 cascade
          negative regulation of release of cytochrome c from mitochondria
          chemical synaptic transmission, postsynaptic
          positive regulation of DNA biosynthetic process
          G-protein coupled receptor binding
          receptor binding
          protein binding
          enzyme binding
          protein domain specific binding
          ubiquitin protein ligase binding
          alpha-1A adrenergic receptor binding
          alpha-1B adrenergic receptor binding
          angiotensin receptor binding
          type 1 angiotensin receptor binding
          D1 dopamine receptor binding
          follicle-stimulating hormone receptor binding
          type 2A serotonin receptor binding
          platelet activating factor receptor binding
          protein complex binding
          protein complex scaffold
          protein kinase B binding
          mitogen-activated protein kinase binding
          14-3-3 protein binding

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