Case Study

Chronic Obstructive Pulmonary Disease (COPD) vs. Heart Failure (HF) vs. Bacterial Pneumonia (PNA): What is the Diagnosis This Time? 


Michael R. Broyles
PharmD – Director of Medical Affairs, Thermo Fisher Scientific



*NT-proBNP values vary by manufacturer and are age dependent, thus the, +2, +3, etc. are times the normal values.
AECOPD: acute exacerbation of chronic obstructive pulmonary disease.
SOB: shortness of breath.
WNL: within normal limit.

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Key Takeaway

Takeaway

Takeaway

In these scenarios, utilizing PCT in the differential diagnosis can lead to appropriate antibiotic treatment decisions for each separate admission.



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References
  1. Klein EY, Monteforte B, Gupta A, Jiang W, May L, Hsieh YH, et al. The frequency of influenza and bacterial coinfection: a systematic review and meta-analysis. Influenza Other Respir Viruses. 2016 Sep;10(5):394-403.
  2. Triposkiadis F, Giamouzis G, Parissis J, Starling RC, Boudoulas H, Skoularigis J, et al. Reframing the association and significance of co-morbidities in heart failure. Eur J Heart Fail. 2016 Jul;18(7):744-58.