Choose B·R·A·H·M·S PCT:

Clinical Significance of Procalcitonin: Evidence Matters

The combination of superior sensitivity and specificity and fast kinetics is what sets PCT apart from other biomarkers when assessing bacterial infection and its severity. But not all PCT tests are the same; it’s important to know how to identify a PCT assay that sustains improvement of patient care through proven clinical, economic, and analytical performance. Only B·R·A·H·M·S PCT^TM assays offer a substantial amount of clinical evidence and alignment to a gold standard, ensuring continuous clinical performance.^{1, 2}

PCT has been extensively documented in over 10,000 publications³, including reviews, clinical trials, meta-analyses, experts’ consensus⁴ and international and national guidelines. Almost all this evidence has been generated using Thermo Scientific^TM B·R·A·H·M·S PCT^TM assays.

This strong evidence from reproducible, randomized clinical trials supports the effectiveness and safety of PCT-aided antibiotic stewardship protocols, for which only B·R·A·H·M·S PCT has an approved indication. 

The Importance of PCT Quality and Evidence: Put Your Patients First

B·R·A·H·M·S PCT-aided algorithms are used to help reduce antibiotic prescriptions, deescalate therapy when appropriate and tailor the therapy duration to individual patient needs. This reduction of antibiotic exposure can benefit in shortening hospital stays, lowering antibiotic resistance and improving outcomes. In addition to improving patient care, B·R·A·H·M·S PCT allows for significant savings in healthcare costs.

PCT cut-offs and clinical algorithms were established using the global reference standard assay: B·R·A·H·M·S PCT Gold Standard.

Through alignment to a validated Gold Standard, B·R·A·H·M·S PCT assays ensure reliable clinical performance in multiple indications², making them the safe choice for patient assessment.

With a high-quality PCT test, clinicians can:

• Minimize the chances of missing a bacterial infection because of false results.
• Feel confident that they are providing the right level of care.
• Ensure customized antibiotic treatment to support stewardship. 

When saving lives, quality is a necessity not to be compromised.