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Gibco
Mouse VEGF-165, AOF Recombinant Protein
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Product Details
RP-87761
Product Specifications
Expression System
E. coli
Class
Recombinant
Type
Protein
Conjugate
Form
Lyophilized
Amount
25 µg
Storage conditions
-20°C
Shipping conditions
Wet ice
Product Specific Information
Reconstitute using 0.1 mg/mL sterile water
Animal Origin Free
Target Information
The vascular endothelial growth factor (VEGF) family currently includes VEGF-A, VEGF-B, VEGF-C, VEGF-D, VEGF-E, and PIGF. VEGF and its receptor system have been shown to be the fundamental regulators in the cell signaling of angiogenesis. Most tumors have the absolute requirement of angiogenesis and VEGF has been described as the most potent angiogenic cytokine linked to this process. To date 5 different isoforms of VEGF have been described. These isoforms are generated as the result of alternative splicing from a single VEGF gene. These various isoforms have been shown to bind to two tyrosine-kinase receptors flt-1 (VEGFR-1) and flk-1/KDR (VEGFR-2), which have been found to be expressed almost exclusively on endothelial cells.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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