EVOS FL Cell Imaging System
Revolutionizing fluorescence microscopy
The powerful yet easy-to-use Invitrogen EVOS FL Cell Imaging System provides the flexibility to fit most epifluorescence microscopy applications. Combining precision components with unique design functionality, the EVOS FL Cell Imaging System has revolutionized fluorescence microscopy.
See our gallery of beautiful images taken with the EVOS FL Cell Imaging System.
Find the perfect light cube and reagent combination using our EVOS Light Cube selection guide.
Get the full experience by requesting an in-lab demo from one of our trained representatives.
EVOS imaging systems brochure
See the entire portfolio of easy to use cell imaging instruments that can be configured with a variety of objectives, light cubes, and vessel holders to meet your research needs.
EVOS FL Cell Imaging System Specs
| Attribute | EVOS FL Detail | ||
|---|---|---|---|
| Illumination | Adjustable-intensity LED (>50,000-hour life per light cube) | ||
| Contrast methods | Epifluorescence and transmitted light (bright field and phase contrast) | ||
| Objective turret | 5-position, front-mounted control | ||
| Fluorescence channels | Simultaneously accommodates up to 4 fluorescent light cubes | ||
| Condenser | Includes 3 positions, with bright-field and phase-contrast annuli | ||
| Condenser working distance | 60 mm | ||
| Stage | Mechanical “glide” stage with X-Y axis fine-positioning controls Interchangeable vessel holders available |
||
| LCD display | 15” high-resolution (1,024 x 768 pixels) color monitor with adjustable tilt | ||
| Cameras |
|
||
| Captured images |
|
||
| Output ports | 3 USB ports, 1 DVI port (supports direct output to USB and networked storage) | ||
| Thermo Fisher Cloud |
Save files to Cloud through computer
|
||
| Power supply | AC adaptor | ||
| Dimensions | Height: 578 mm (22.8 in) Depth: 470 mm (18.5 in) Width: 355 mm (14.0 in) |
||
| Weight | 15.3 kg (33.7 lb) |
EVOS FL Cell Imaging System Citations
- Adams Y and Rowe JA (2013) The Effect of Anti-Rosetting Agents against Malaria Parasites under Physiological Flow Conditions. PLoS ONE 8(9): e73999.
- Becalska AN et al. (2013) Formation of membrane ridges and scallops by the F-BAR protein Nervous Wreck. Mol Biol Cell 24(15):2406-2418.
- Beckley JT et al. (2013) Medial Prefrontal Cortex Inversely Regulates Toluene-Induced Changes in Markers of Synaptic Plasticity of Mesolimbic Dopamine Neurons. J Neurosci 33(2):804-813.
- Bennett DC et al. (2013) High-throughput Screening Identifies Aclacinomycin as a Radiosensitizer of EGFR-Mutant Non-Small Cell Lung Cancer. Transl Oncol 6(3): 382-391.
- Bournine L et al. (2013) Revealing the anti-tumoral effect of Algerian Glaucium flavum roots against human cancer cells. Phytomedicine 20(13):1211-1218.
- Businaro L et al. (2013) Cross talk between cancer and immune cells: exploring complex dynamics in a microfluidic environment. Lab Chip 13:229-239.
- Chang NJ et al. (2013) The Effect of Osteochondral Regeneration Using Polymer Constructs and Continuous Passive Motion Therapy in the Lower Weight-Bearing Zone of Femoral Trocheal Groove in Rabbits. Ann Biomed Eng 41(2):385-397.
- Chang VT et al. (2013) Synergism between fibronectin and transforming growth factor-β1 in the production of substance P in monocytes of patients with myelofibrosis. Leuk Lymph 54(3):631-638.
- Chen W et al. (2013) New fluorescent probes for sulfane sulfurs and the application in bioimaging. Chem Sci 4: 2892-2896.
- Chen WT et al. (2013) Systemic identification of functional residues in mammalian histone H2AX. Mol Cell Biol 33(1):111–126.
- Currie SM et al. (2013) The Human Cathelicidin LL-37 Has Antiviral Activity against Respiratory Syncytial Virus. PLoS ONE 8(8):e73659. doi:10.1371/journal.pone.0073659.
- DePorter SM et al. (2013) A Protein Transduction Domain with Cell Uptake and Selectivity Profiles that Are Controlled by Multivalency Effects. Chem Biol 20(3):434-444.
- Duarte MS et al. (2013) Enhancement of adipogenesis and fibrogenesis in skeletal muscle of Wagyu compared with Angus cattle. J Anim Sci 91(6):2938-2946.
- Dyo YM et al. (2013) Evaluating new isolates of microalgae from Kazakhstan for biodiesel production. Russ J Plant Phys 60(4):549-554.
- Focant MC et al. (2013) PICK1 expression in reactive astrocytes within the spinal cord of amyotrophic lateral sclerosis (ALS) rats. Neuropath App Neurobio 39(3):231–242.
- Goedeke L et al. (2013) A Regulatory Role for MicroRNA 33* in Controlling Lipid Metabolism Gene Expression. Mol Cell Biol 33:2339-2352.
- Goswami R et al. (2013) Viral degradosome hijacks mitochondria to suppress innate immunity. Cell Res 23:1025-1042.
- Griffiths S et al. (2013) Human platelet lysate stimulates high-passage and senescent human multipotent mesenchymal stromal cell growth and rejuvenation in vitro. Cytotherapy doi:10.1016/j.jcyt.2013.05.020.
- Hauser MJ et al. (2013) Antiviral Responses by Swine Primary Bronchoepithelial Cells Are Limited Compared to Human Bronchoepithelial Cells Following Influenza Virus Infection. PLoS ONE 8(7): e70251. doi:10.1371/journal.pone.0070251.
- Hwang I et al. (2013) Neural stem cells inhibit melanin production by activation of Wnt inhibitors. J Dermatol Sci doi: 10.1016/j.jdermsci.2013.08.006.
- Johnson ES et al. (2013) Metabolomic Profiling Reveals a Role for Caspase-2 in Lipoapoptosis. J Biol Chem 288: 14463-14475.
- Jun Y et al. (2013) Microfluidics-generated pancreatic islet microfibers for enhanced immunoprotection. Biomaterials 34(33):8122-8130.
- Lerner C et al. (2013) Reduced mammalian target of rapamycin activity facilitates mitochondrial retrograde signaling and increases life span in normal human fibroblasts. Aging Cell doi: 10.1111/acel.12122.
- Li C et al. (2013) Manipulation of the Porcine Epidemic Diarrhea Virus Genome Using Targeted RNA Recombination. PLoS ONE 8(8): e69997. doi:10.1371/journal.pone.0069997.
- Liberski AR et al. (2013) Adaptation of a Commonly Used, Chemically Defined Medium for Human Embryonic Stem Cells to Stable Isotope Labeling with Amino Acids in Cell Culture. J Prot Res 12(7):3233–3245.
- Liu B et al. (2013) Overexpression of parkin in the rat nigrostriatal dopamine system protects against methamphetamine neurotoxicity. Exp Neur 247:359–372.
- Marsh GA et al. (2013) Recombinant Hendra viruses expressing a reporter gene retain pathogenicity in ferrets. Virol J10:95.
- Mizrahi B et al. (2013) Long-Lasting Antifouling Coating from Multi-Armed Polymer. Langmuir 29 (32):10087–10094.
- Mooney AJ et al. (2013) Recombinant PIV5 vaccine encoding the influenza hemagglutinin protects against H5N1 highly pathogenic avian influenza virus infection following intranasal or intramuscular vaccination of BALB/c mice. J Virol 87(1):363–371.
- Nakamura R et al. (2013) Contrasting effect of perlecan on adipogenic and osteogenic differentiation of mesenchymal stem cells in vitro. Anim Sci Jdoi:10.1111/asj.12116.
- Owa C et al. (2013) Triptolide induces lysosomal-mediated programmed cell death in MCF-7 breast cancer cells. Int J Womens Health 5:557–569.
- Patel N et al. (2013) Reducing Influenza Virus Infection through shRNA Targeting TMPRSS2 Protease. J Youn Investig 25(3):32-37.
- Penrose HM et al. (2013) Spermidine stimulates T-cell protein tyrosine phosphatase-mediated protection of intestinal epithelial barrier function. J Biol Chem doi:10.1074/jbc.M113.475962.
- Pritchard SM et al. (2013) Analysis of Herpes Simplex Virion Tegument ICP4 Derived from Infected Cells and ICP4-Expressing Cells. PLoS ONE 8(8):e70889. doi:10.1371/journal.pone.0070889.
- Rauert-Wunderlich H et al. (2013) The IKK Inhibitor Bay 11-7082 Induces Cell Death Independent from Inhibition of Activation of NFκB Transcription Factors. PLoS ONE 8(3):e59292. doi:10.1371/journal.pone.0059292.
- Rodriguez-Ortiz CJ et al. (2013) Neuronal-Specific Overexpression of a Mutant Valosin - Containing Protein Associated with IBMPFD Promotes Aberrant Ubiquitin and TDP-43 Accumulation and Cognitive Dysfunction in Transgenic Mice. Am J Pathol 183(2):504–515.
- Selvaraj V et al. (2013) Arsenic trioxide (As2O3) induces apoptosis and necrosis mediated cell death through mitochondrial membrane potential damage and elevated production of reactive oxygen species in PLHC-1 fish cell line. Chemosphere 90(3):1201–1209.
- Selvaraj V et al. (2013) Selenium (sodium selenite) causes cytotoxicity and apoptotic mediated cell death in PLHC-1 fish cell line through DNA and mitochondrial membrane potential damage. Ecotoxicol Environ Saf 87(1):80–88.
- Shak JR et al. (2013) Novel Role for the Streptococcus pneumoniae Toxin Pneumolysin in the Assembly of Biofilms. mBio 4(5): e00655-13.
- Sreevalsan S and S Safe (2013) The Cannabinoid WIN 55,212-2 Decreases Specificity Protein (Sp) Transcription Factors and the Oncogenic Cap Protein eIF4E in Colon Cancer Cells. Mol Cancer Ther doi:10.1158/1535-7163.MCT-13-0486.
- Tavares MB et al. (2013) Bacillus subtilis Endospores at High Purity and Recovery Yields: Optimization of Growth Conditions and Purification Method. Curr Microbiol 66(3):279-285.
- Titler AM et al. (2013) Astrocyte plasticity revealed by adaptations to severe proteotoxic stress. Cell Tissue Res 352(3):427-443.
- Toscano MG et al. (2013) Use of zinc-finger nucleases to knock out the WAS gene in K562 cells: a human cellular model for Wiskott-Aldrich syndrome. Dis Model Mech 6(2)544-554.
- Vanharanta S et al. (2013) Epigenetic expansion of VHL-HIF signal output drives multiorgan metastasis in renal cancer. Nat Med 19:50–56.
- Vashisth P et al. (2013) Antibiofilm activity of quercetin-encapsulated cytocompatible nanofibers against Candida albicans. J Bioact Compat Polym doi:10.1177/0883911513502279.
- Wang J et al. (2013) Cadherin-17 induces tumorigenesis and lymphatic metastasis in gastric cancer through activation of NFκB signaling pathway. Cancer Biol Ther 14(3):262–270.
- Wang X et al. (2013) Optimisation and Use of Humanised RBL NF-AT-GFP and NF-AT-DsRed Reporter Cell Lines Suitable for High-Throughput Scale Detection of Allergic Sensitisation in Array Format and Identification of the ECM–Integrin Interaction as Critical Factor. Mol Biotechnol doi:10.1007/s12033-013-9689-x
- Wang Y et al. (2013) Bioactive Lipids-Based pH Sensitive Micelles for Co-Delivery of Doxorubicin and Ceramide to Overcome Multidrug Resistance in Leukemia. Pharm Res doi: 10.1007/s11095-013-1121-5.
- Wang Z et al. (2013) Elevated transcriptional co-activator p102 mediates angiotensin II type 1 receptor up-regulation and extracellular matrix overproduction in the high glucose-treated rat glomerular mesangial cells and isolated glomeruli. Eur J Pharm 702:208–217.
- Willmann CA et al. (2013) To Clone or Not to Clone? Induced Pluripotent Stem Cells Can Be Generated in Bulk Culture. PLoS ONE 8(5): e65324. doi:10.1371/journal.pone.0065324.
- Youngstrom DW et al. (2013) Functional Characterization of Detergent-Decellularized Equine Tendon Extracellular Matrix for Tissue Engineering Applications. PLoS ONE 8(5): e64151. doi:10.1371/journal.pone.0064151.
- Zägel P et al. (2013) The Dimerization Domain in Outer Segment Guanylate Cyclase Is a Ca2+-Sensitive Control Switch Module. Biochemistry 52(30):5065–5074.
- Zhu S et al. (2013) Highly water-soluble BODIPY-based fluorescent probes for sensitive fluorescent sensing of zinc(II). J Mater Chem B 1:1722-1728.
- Beckley JT et al. (2013) Medial prefrontal cortex inversely regulates toluene-induced changes in markers of synaptic plasticity of mesolimbic dopamine neurons. J Neurosci 33(2):804–813.
- Chen WT et al. (2013) Systemic identification of functional residues in mammalian histone H2AX. Mol Cell Biol 33(1):111–126.
- Mooney AJ et al. (2013) Recombinant PIV5 vaccine encoding the influenza hemagglutinin protects against H5N1 highly pathogenic avian influenza virus infection following intranasal or intramuscular vaccination of BALB/c mice. J Virol 87(1):363–371.
- O’Flynn NMJ et al. (2013) Improving promiscuous mammalian cell entry by the baculovirus Autographa californica multiple nuclear polyhedrosis virus. Biosci Rep doi:10.1042/BSR20120093
- Selvaraj V et al. (2013) Arsenic trioxide (As2O3) induces apoptosis and necrosis mediated cell death through mitochondrial membrane potential damage and elevated production of reactive oxygen species in PLHC-1 fish cell line. Chemosphere 90(3):1201–1209.
- Selvaraj V et al. (2013) Selenium (sodium selenite) causes cytotoxicity and apoptotic mediated cell death in PLHC-1 fish cell line through DNA and mitochondrial membrane potential damage. Ecotoxicol Environ Saf 87(1):80–88.
- Vanharanta S et al. (2013) Epigenetic expansion of VHL-HIF signal output drives multiorgan metastasis in renal cancer. Nat Med 19:50–56.
- Wang J et al. (2013) Cadherin-17 induces tumorigenesis and lymphatic metastasis in gastric cancer through activation of NFκB signaling pathway. Cancer Biol Ther 14(3):262–270.
- Baraniak PR et al. (2012) Stiffening of human mesenchymal stem cell spheroid microenvironments induced by incorporation of gelatin microparticles. J Mech Behav Biomed Mater 11:63–71.
- Berger JV et al. (2012) Opposite regulation of metabotropic glutamate receptor 3 and metabotropic glutamate receptor 5 by inflammatory stimuli in cultured microglia and astrocytes. Neuroscience 205:29–38.
- Borjigin M et al. (2012) Proliferation of genetically modified human cells on electrospun nanofiber scaffolds. Mol Ther Nucleic Acids doi:10.1038/mtna.2012.51.
- Chang NJ et al. (2012) The effect of osteochondral regeneration using polymer constructs and continuous passive motion therapy in the lower weight-bearing zone of femoral trocheal groove in rabbits. Ann Biomed Eng 41(2):385–397.
- Chen CL et al. (2012) Single-cell analysis of circulating tumor cells identifies cumulative expression patterns of EMT-related genes in metastatic prostate cancer. Prostate doi:10.1002/pros.22625
- Cheng D. et al. (2012). Kinetic analysis of porcine fibroblast reprogramming toward pluripotency by defined factors. Cellular Reprogram 14(4):312–323.
- Dammanahalli KJ et al. (2012) Vanin-1 pantetheinase drives smooth muscle cell activation in post-arterial injury neointimal hyperplasia. PLoS ONE 7(6): e39106. doi:10.1371/journal.pone.0039106
- deBoer SM et al. (2012) Acid-activated structural reorganization of the Rift Valley fever virus Gc fusion protein. J Virol 86(24):13642–13652.
- deBoer SM et al. (2012) Heparin sulfate facilitates Rift Valley fever virus entry into the cell. J Virol 86(24):13767–13773.
- Focant MC et al. (2012) Differential regulation of C-terminal splice variants of the glutamate transporter GLT-1 by tumor necrosis factor-alpha in primary cultures of astrocytes. Neurochem Int 58(7):751–758.
- Focant MC et al. (2013) PICK1 expression in reactive astrocytes within the spinal cord of ALS rats. Neuropathol Appl Neurobiol 39(3):231–242. doi:10.1111/j.1365-2990.2012.01282.x.
- Grandinetti G et al. (2012) Exploring the mechanism of plasmid DNA nuclear internalization with polymer-based vehicles. Mol Pharm 9(8):2256–2267.
- Grandinetti G et al. (2012) Membrane and nuclear permeabilization by polymeric pDNA vehicles: efficient method for gene delivery or mechanism of cytotoxicity? Mol Pharm 9(3):523–538.
- Hemp ST et al. (2012) Phosphonium-containing diblock copolymers for enhanced colloidal stability and efficient nucleic acid delivery. Biomacromolecules 13(8):2439–2445.
- Horst D et al. (2012) The “bridge” in the Epstein-Barr Virus alkaline exonuclease protein BGLF5 contributes to shutoff activity during productive infection. J Virol 86(17):9175–9187.
- Hsieh T-J et al. (2012) Melamine induces human renal proximal tubular cell injury via transforming growth factor-beta and oxidative stress. Toxicol Sci 130(1):17–32.
- Hu J et al. (2012) Vitamin C enhances the in vitro development of porcine pre-implantation embryos by reducing oxidative stress. Reprod Domest Anim 47(6):873–879.
- Janardhana V et al. (2012) Cloning, expression and antiviral activity of IFNγ from the Australian fruit bat, Pteropus alecto. Dev Comp Immunol 36(3):610–618.
- Mescola A et al. (2012) Probing cytoskeleton organisation of neuroblastoma cells with single-cell force spectroscopy. J Mol Recognit 25(5):270–277.
- Meissner S et al. (2013) Microcystin production revisited: conjugate formation makes a major contribution. Environ Microbiol doi:10.1111/1462-2920.12072.
- Mizrahi B et al. (2012) A stiff injectable biodegradable elastomer. Adv Funct Mater 23(12):1527–1533. doi:10.1002/adfm.201202433.
- Ohno M et al. (2012) Astaxanthin rich crude extract of Haematococcus pluvialis induces cytochrome P450 1A1 mRNA by activating aryl hydrocarbon receptor in rat hepatoma H4IIE cells. Food Chem 130(2):356–361.
- Ohno M et al. (2012) Sudan III dye strongly induces CYP1A1 mRNA expression in HepG2 cells. J Biochem Mol Toxicol 26(1):16–22.
- Prowse ABJ et al. (2012) Analysis of mitochondrial function and localisation during human embryonic stem cell differentiation in vitro. PLoS ONE 7(12):e52214. doi:10.1371/journal.pone.0052214
- Ranaldi G et al. (2012) Intracellular zinc is required for intestinal cell survival signals triggered by the inflammatory cytokine TNFα. J Nutr Biochem doi:10.1016/j.jnutbio.2012.06.020
- Roberts BLT et al. (2012) Role of disulfide cross-linking of mutant SOD1 in the formation of inclusion-body-like structures. PLoS ONE 7(10):e47838. doi:10.1371/journal.pone.0047838.
- Ramonet D et al. (2012) PARK9-associated ATP13A2 localizes to intracellular acidic vesicles and regulates cation homeostasis and neuronal integrity. Human Mol Gen 21(8):1725–1743.
- Schäfer S et al. (2012) Immunomodulatory influence of bone marrow-derived mesenchymal stem cells on neuroinflammation in astrocyte cultures. J Neuroimmunol 249(1):40–48.
- Sheikholeslam M et al. (2012) Dispersion of multiwalled carbon nanotubes in water using ionic-complementary peptides. Langmuir 28(34):12550–12556.
- Urbanska AM et al. (2012) Therapeutic effect of orally administered microencapsulated oxaliplatin for colorectal cancer. Biomaterials 33(18):4752–4761.
- Van de Vijver E et al. (2012) Defects in Glanzmann thrombasthenia and LAD-III (LAD-1/v) syndrome: the role of integrin β1 and β3 in platelet adhesion to collagen. Blood 119(2):583–586.
- Wang Y et al. (2012) Oxidized phospholipid based pH sensitive micelles for delivery of anthracyclines to resistant leukemia cells in vitro. Int J Pharm 422(1–2):409–417.
- Wang D et al. (2012) Phytochemicals attenuating aberrant activation of β-catenin in cancer cells. PLoS ONE 7(12): e50508. doi:10.1371/journal.pone.0050508
- Weimar CHE et al. (2012) Endometrial stromal cells of women with recurrent miscarriage fail to discriminate between high- and low-quality human embryos. PLoS ONE 7(7):e41424. doi:10.1371/journal.pone.0041424
- Zhan M et al. (2012) The B-MYB transcriptional network guides cell cycle progression and fate decisions to sustain self-renewal and the identity of pluripotent stem cells. PLoS ONE 7(8):e42350. doi:10.1371/journal.pone.0042350
- Curatola AM et al. (2011) Cyclic GMP protects endothelial progenitors from oxidative stress. Angiogenesis 14(3):267–279.
- Hellmann J et al. (2011) Resolvin D1 decreases adipose tissue macrophage accumulation and improves insulin. FASEB J 25:2399-2407.
- Kachadourian R et al. (2011) 2′,5′-Dihydroxychalcone-induced glutathione is mediated by oxidative stress and kinase signaling pathways. Free Radic Biol Med 51(6):1146–1154.
- Krajewska M et al. (2011) Neuronal deletion of caspase 8 protects against brain injury in mouse models of controlled cortical impact and kainic acid-induced excitotoxicty. PLoS ONE 6(9):1–21.
- Lim P et al. (2011) Gap junction-mediated import of microRNA from bone marrow stromal cells can elicit cell cycle quiescence in breast cancer cells. Cancer Res 71:1550–1560.
- Lu C et al. (2011) TLR2 ligand induces protection against cerebral ischemia/reperfusion injury via activation of phosphoinositide 3-kinase/Akt signaling. J Immunol 187(3):1458–1466.
- Eijkelkamp N et al. (2010) Low nociceptor GRK2 prolongs prostaglandin E2 hyperalgesia via biased cAMP signaling to Epac/Rap1, protein kinase Cε, and MEK/ERK. J Neurosci 30(38):12806–12815.
- Smeenk G et al. (2010) The NuRD chromatin–remodeling complex regulates signaling and repair of DNA damage. J Cell Bio 190(5):741–749.
- Wang H et al. (2010) Tissue factor-dependent procoagulant activity of subtilase cytotoxin, a potent AB5 toxin produced by Shiga toxigenic Escherichia coli. J Infect Dis 202(9):1415–1423.
EVOS FL Cell Imaging System Specs
| Attribute | EVOS FL Detail | ||
|---|---|---|---|
| Illumination | Adjustable-intensity LED (>50,000-hour life per light cube) | ||
| Contrast methods | Epifluorescence and transmitted light (bright field and phase contrast) | ||
| Objective turret | 5-position, front-mounted control | ||
| Fluorescence channels | Simultaneously accommodates up to 4 fluorescent light cubes | ||
| Condenser | Includes 3 positions, with bright-field and phase-contrast annuli | ||
| Condenser working distance | 60 mm | ||
| Stage | Mechanical “glide” stage with X-Y axis fine-positioning controls Interchangeable vessel holders available |
||
| LCD display | 15” high-resolution (1,024 x 768 pixels) color monitor with adjustable tilt | ||
| Cameras |
|
||
| Captured images |
|
||
| Output ports | 3 USB ports, 1 DVI port (supports direct output to USB and networked storage) | ||
| Thermo Fisher Cloud |
Save files to Cloud through computer
|
||
| Power supply | AC adaptor | ||
| Dimensions | Height: 578 mm (22.8 in) Depth: 470 mm (18.5 in) Width: 355 mm (14.0 in) |
||
| Weight | 15.3 kg (33.7 lb) |
EVOS FL Cell Imaging System Citations
- Adams Y and Rowe JA (2013) The Effect of Anti-Rosetting Agents against Malaria Parasites under Physiological Flow Conditions. PLoS ONE 8(9): e73999.
- Becalska AN et al. (2013) Formation of membrane ridges and scallops by the F-BAR protein Nervous Wreck. Mol Biol Cell 24(15):2406-2418.
- Beckley JT et al. (2013) Medial Prefrontal Cortex Inversely Regulates Toluene-Induced Changes in Markers of Synaptic Plasticity of Mesolimbic Dopamine Neurons. J Neurosci 33(2):804-813.
- Bennett DC et al. (2013) High-throughput Screening Identifies Aclacinomycin as a Radiosensitizer of EGFR-Mutant Non-Small Cell Lung Cancer. Transl Oncol 6(3): 382-391.
- Bournine L et al. (2013) Revealing the anti-tumoral effect of Algerian Glaucium flavum roots against human cancer cells. Phytomedicine 20(13):1211-1218.
- Businaro L et al. (2013) Cross talk between cancer and immune cells: exploring complex dynamics in a microfluidic environment. Lab Chip 13:229-239.
- Chang NJ et al. (2013) The Effect of Osteochondral Regeneration Using Polymer Constructs and Continuous Passive Motion Therapy in the Lower Weight-Bearing Zone of Femoral Trocheal Groove in Rabbits. Ann Biomed Eng 41(2):385-397.
- Chang VT et al. (2013) Synergism between fibronectin and transforming growth factor-β1 in the production of substance P in monocytes of patients with myelofibrosis. Leuk Lymph 54(3):631-638.
- Chen W et al. (2013) New fluorescent probes for sulfane sulfurs and the application in bioimaging. Chem Sci 4: 2892-2896.
- Chen WT et al. (2013) Systemic identification of functional residues in mammalian histone H2AX. Mol Cell Biol 33(1):111–126.
- Currie SM et al. (2013) The Human Cathelicidin LL-37 Has Antiviral Activity against Respiratory Syncytial Virus. PLoS ONE 8(8):e73659. doi:10.1371/journal.pone.0073659.
- DePorter SM et al. (2013) A Protein Transduction Domain with Cell Uptake and Selectivity Profiles that Are Controlled by Multivalency Effects. Chem Biol 20(3):434-444.
- Duarte MS et al. (2013) Enhancement of adipogenesis and fibrogenesis in skeletal muscle of Wagyu compared with Angus cattle. J Anim Sci 91(6):2938-2946.
- Dyo YM et al. (2013) Evaluating new isolates of microalgae from Kazakhstan for biodiesel production. Russ J Plant Phys 60(4):549-554.
- Focant MC et al. (2013) PICK1 expression in reactive astrocytes within the spinal cord of amyotrophic lateral sclerosis (ALS) rats. Neuropath App Neurobio 39(3):231–242.
- Goedeke L et al. (2013) A Regulatory Role for MicroRNA 33* in Controlling Lipid Metabolism Gene Expression. Mol Cell Biol 33:2339-2352.
- Goswami R et al. (2013) Viral degradosome hijacks mitochondria to suppress innate immunity. Cell Res 23:1025-1042.
- Griffiths S et al. (2013) Human platelet lysate stimulates high-passage and senescent human multipotent mesenchymal stromal cell growth and rejuvenation in vitro. Cytotherapy doi:10.1016/j.jcyt.2013.05.020.
- Hauser MJ et al. (2013) Antiviral Responses by Swine Primary Bronchoepithelial Cells Are Limited Compared to Human Bronchoepithelial Cells Following Influenza Virus Infection. PLoS ONE 8(7): e70251. doi:10.1371/journal.pone.0070251.
- Hwang I et al. (2013) Neural stem cells inhibit melanin production by activation of Wnt inhibitors. J Dermatol Sci doi: 10.1016/j.jdermsci.2013.08.006.
- Johnson ES et al. (2013) Metabolomic Profiling Reveals a Role for Caspase-2 in Lipoapoptosis. J Biol Chem 288: 14463-14475.
- Jun Y et al. (2013) Microfluidics-generated pancreatic islet microfibers for enhanced immunoprotection. Biomaterials 34(33):8122-8130.
- Lerner C et al. (2013) Reduced mammalian target of rapamycin activity facilitates mitochondrial retrograde signaling and increases life span in normal human fibroblasts. Aging Cell doi: 10.1111/acel.12122.
- Li C et al. (2013) Manipulation of the Porcine Epidemic Diarrhea Virus Genome Using Targeted RNA Recombination. PLoS ONE 8(8): e69997. doi:10.1371/journal.pone.0069997.
- Liberski AR et al. (2013) Adaptation of a Commonly Used, Chemically Defined Medium for Human Embryonic Stem Cells to Stable Isotope Labeling with Amino Acids in Cell Culture. J Prot Res 12(7):3233–3245.
- Liu B et al. (2013) Overexpression of parkin in the rat nigrostriatal dopamine system protects against methamphetamine neurotoxicity. Exp Neur 247:359–372.
- Marsh GA et al. (2013) Recombinant Hendra viruses expressing a reporter gene retain pathogenicity in ferrets. Virol J10:95.
- Mizrahi B et al. (2013) Long-Lasting Antifouling Coating from Multi-Armed Polymer. Langmuir 29 (32):10087–10094.
- Mooney AJ et al. (2013) Recombinant PIV5 vaccine encoding the influenza hemagglutinin protects against H5N1 highly pathogenic avian influenza virus infection following intranasal or intramuscular vaccination of BALB/c mice. J Virol 87(1):363–371.
- Nakamura R et al. (2013) Contrasting effect of perlecan on adipogenic and osteogenic differentiation of mesenchymal stem cells in vitro. Anim Sci Jdoi:10.1111/asj.12116.
- Owa C et al. (2013) Triptolide induces lysosomal-mediated programmed cell death in MCF-7 breast cancer cells. Int J Womens Health 5:557–569.
- Patel N et al. (2013) Reducing Influenza Virus Infection through shRNA Targeting TMPRSS2 Protease. J Youn Investig 25(3):32-37.
- Penrose HM et al. (2013) Spermidine stimulates T-cell protein tyrosine phosphatase-mediated protection of intestinal epithelial barrier function. J Biol Chem doi:10.1074/jbc.M113.475962.
- Pritchard SM et al. (2013) Analysis of Herpes Simplex Virion Tegument ICP4 Derived from Infected Cells and ICP4-Expressing Cells. PLoS ONE 8(8):e70889. doi:10.1371/journal.pone.0070889.
- Rauert-Wunderlich H et al. (2013) The IKK Inhibitor Bay 11-7082 Induces Cell Death Independent from Inhibition of Activation of NFκB Transcription Factors. PLoS ONE 8(3):e59292. doi:10.1371/journal.pone.0059292.
- Rodriguez-Ortiz CJ et al. (2013) Neuronal-Specific Overexpression of a Mutant Valosin - Containing Protein Associated with IBMPFD Promotes Aberrant Ubiquitin and TDP-43 Accumulation and Cognitive Dysfunction in Transgenic Mice. Am J Pathol 183(2):504–515.
- Selvaraj V et al. (2013) Arsenic trioxide (As2O3) induces apoptosis and necrosis mediated cell death through mitochondrial membrane potential damage and elevated production of reactive oxygen species in PLHC-1 fish cell line. Chemosphere 90(3):1201–1209.
- Selvaraj V et al. (2013) Selenium (sodium selenite) causes cytotoxicity and apoptotic mediated cell death in PLHC-1 fish cell line through DNA and mitochondrial membrane potential damage. Ecotoxicol Environ Saf 87(1):80–88.
- Shak JR et al. (2013) Novel Role for the Streptococcus pneumoniae Toxin Pneumolysin in the Assembly of Biofilms. mBio 4(5): e00655-13.
- Sreevalsan S and S Safe (2013) The Cannabinoid WIN 55,212-2 Decreases Specificity Protein (Sp) Transcription Factors and the Oncogenic Cap Protein eIF4E in Colon Cancer Cells. Mol Cancer Ther doi:10.1158/1535-7163.MCT-13-0486.
- Tavares MB et al. (2013) Bacillus subtilis Endospores at High Purity and Recovery Yields: Optimization of Growth Conditions and Purification Method. Curr Microbiol 66(3):279-285.
- Titler AM et al. (2013) Astrocyte plasticity revealed by adaptations to severe proteotoxic stress. Cell Tissue Res 352(3):427-443.
- Toscano MG et al. (2013) Use of zinc-finger nucleases to knock out the WAS gene in K562 cells: a human cellular model for Wiskott-Aldrich syndrome. Dis Model Mech 6(2)544-554.
- Vanharanta S et al. (2013) Epigenetic expansion of VHL-HIF signal output drives multiorgan metastasis in renal cancer. Nat Med 19:50–56.
- Vashisth P et al. (2013) Antibiofilm activity of quercetin-encapsulated cytocompatible nanofibers against Candida albicans. J Bioact Compat Polym doi:10.1177/0883911513502279.
- Wang J et al. (2013) Cadherin-17 induces tumorigenesis and lymphatic metastasis in gastric cancer through activation of NFκB signaling pathway. Cancer Biol Ther 14(3):262–270.
- Wang X et al. (2013) Optimisation and Use of Humanised RBL NF-AT-GFP and NF-AT-DsRed Reporter Cell Lines Suitable for High-Throughput Scale Detection of Allergic Sensitisation in Array Format and Identification of the ECM–Integrin Interaction as Critical Factor. Mol Biotechnol doi:10.1007/s12033-013-9689-x
- Wang Y et al. (2013) Bioactive Lipids-Based pH Sensitive Micelles for Co-Delivery of Doxorubicin and Ceramide to Overcome Multidrug Resistance in Leukemia. Pharm Res doi: 10.1007/s11095-013-1121-5.
- Wang Z et al. (2013) Elevated transcriptional co-activator p102 mediates angiotensin II type 1 receptor up-regulation and extracellular matrix overproduction in the high glucose-treated rat glomerular mesangial cells and isolated glomeruli. Eur J Pharm 702:208–217.
- Willmann CA et al. (2013) To Clone or Not to Clone? Induced Pluripotent Stem Cells Can Be Generated in Bulk Culture. PLoS ONE 8(5): e65324. doi:10.1371/journal.pone.0065324.
- Youngstrom DW et al. (2013) Functional Characterization of Detergent-Decellularized Equine Tendon Extracellular Matrix for Tissue Engineering Applications. PLoS ONE 8(5): e64151. doi:10.1371/journal.pone.0064151.
- Zägel P et al. (2013) The Dimerization Domain in Outer Segment Guanylate Cyclase Is a Ca2+-Sensitive Control Switch Module. Biochemistry 52(30):5065–5074.
- Zhu S et al. (2013) Highly water-soluble BODIPY-based fluorescent probes for sensitive fluorescent sensing of zinc(II). J Mater Chem B 1:1722-1728.
- Beckley JT et al. (2013) Medial prefrontal cortex inversely regulates toluene-induced changes in markers of synaptic plasticity of mesolimbic dopamine neurons. J Neurosci 33(2):804–813.
- Chen WT et al. (2013) Systemic identification of functional residues in mammalian histone H2AX. Mol Cell Biol 33(1):111–126.
- Mooney AJ et al. (2013) Recombinant PIV5 vaccine encoding the influenza hemagglutinin protects against H5N1 highly pathogenic avian influenza virus infection following intranasal or intramuscular vaccination of BALB/c mice. J Virol 87(1):363–371.
- O’Flynn NMJ et al. (2013) Improving promiscuous mammalian cell entry by the baculovirus Autographa californica multiple nuclear polyhedrosis virus. Biosci Rep doi:10.1042/BSR20120093
- Selvaraj V et al. (2013) Arsenic trioxide (As2O3) induces apoptosis and necrosis mediated cell death through mitochondrial membrane potential damage and elevated production of reactive oxygen species in PLHC-1 fish cell line. Chemosphere 90(3):1201–1209.
- Selvaraj V et al. (2013) Selenium (sodium selenite) causes cytotoxicity and apoptotic mediated cell death in PLHC-1 fish cell line through DNA and mitochondrial membrane potential damage. Ecotoxicol Environ Saf 87(1):80–88.
- Vanharanta S et al. (2013) Epigenetic expansion of VHL-HIF signal output drives multiorgan metastasis in renal cancer. Nat Med 19:50–56.
- Wang J et al. (2013) Cadherin-17 induces tumorigenesis and lymphatic metastasis in gastric cancer through activation of NFκB signaling pathway. Cancer Biol Ther 14(3):262–270.
- Baraniak PR et al. (2012) Stiffening of human mesenchymal stem cell spheroid microenvironments induced by incorporation of gelatin microparticles. J Mech Behav Biomed Mater 11:63–71.
- Berger JV et al. (2012) Opposite regulation of metabotropic glutamate receptor 3 and metabotropic glutamate receptor 5 by inflammatory stimuli in cultured microglia and astrocytes. Neuroscience 205:29–38.
- Borjigin M et al. (2012) Proliferation of genetically modified human cells on electrospun nanofiber scaffolds. Mol Ther Nucleic Acids doi:10.1038/mtna.2012.51.
- Chang NJ et al. (2012) The effect of osteochondral regeneration using polymer constructs and continuous passive motion therapy in the lower weight-bearing zone of femoral trocheal groove in rabbits. Ann Biomed Eng 41(2):385–397.
- Chen CL et al. (2012) Single-cell analysis of circulating tumor cells identifies cumulative expression patterns of EMT-related genes in metastatic prostate cancer. Prostate doi:10.1002/pros.22625
- Cheng D. et al. (2012). Kinetic analysis of porcine fibroblast reprogramming toward pluripotency by defined factors. Cellular Reprogram 14(4):312–323.
- Dammanahalli KJ et al. (2012) Vanin-1 pantetheinase drives smooth muscle cell activation in post-arterial injury neointimal hyperplasia. PLoS ONE 7(6): e39106. doi:10.1371/journal.pone.0039106
- deBoer SM et al. (2012) Acid-activated structural reorganization of the Rift Valley fever virus Gc fusion protein. J Virol 86(24):13642–13652.
- deBoer SM et al. (2012) Heparin sulfate facilitates Rift Valley fever virus entry into the cell. J Virol 86(24):13767–13773.
- Focant MC et al. (2012) Differential regulation of C-terminal splice variants of the glutamate transporter GLT-1 by tumor necrosis factor-alpha in primary cultures of astrocytes. Neurochem Int 58(7):751–758.
- Focant MC et al. (2013) PICK1 expression in reactive astrocytes within the spinal cord of ALS rats. Neuropathol Appl Neurobiol 39(3):231–242. doi:10.1111/j.1365-2990.2012.01282.x.
- Grandinetti G et al. (2012) Exploring the mechanism of plasmid DNA nuclear internalization with polymer-based vehicles. Mol Pharm 9(8):2256–2267.
- Grandinetti G et al. (2012) Membrane and nuclear permeabilization by polymeric pDNA vehicles: efficient method for gene delivery or mechanism of cytotoxicity? Mol Pharm 9(3):523–538.
- Hemp ST et al. (2012) Phosphonium-containing diblock copolymers for enhanced colloidal stability and efficient nucleic acid delivery. Biomacromolecules 13(8):2439–2445.
- Horst D et al. (2012) The “bridge” in the Epstein-Barr Virus alkaline exonuclease protein BGLF5 contributes to shutoff activity during productive infection. J Virol 86(17):9175–9187.
- Hsieh T-J et al. (2012) Melamine induces human renal proximal tubular cell injury via transforming growth factor-beta and oxidative stress. Toxicol Sci 130(1):17–32.
- Hu J et al. (2012) Vitamin C enhances the in vitro development of porcine pre-implantation embryos by reducing oxidative stress. Reprod Domest Anim 47(6):873–879.
- Janardhana V et al. (2012) Cloning, expression and antiviral activity of IFNγ from the Australian fruit bat, Pteropus alecto. Dev Comp Immunol 36(3):610–618.
- Mescola A et al. (2012) Probing cytoskeleton organisation of neuroblastoma cells with single-cell force spectroscopy. J Mol Recognit 25(5):270–277.
- Meissner S et al. (2013) Microcystin production revisited: conjugate formation makes a major contribution. Environ Microbiol doi:10.1111/1462-2920.12072.
- Mizrahi B et al. (2012) A stiff injectable biodegradable elastomer. Adv Funct Mater 23(12):1527–1533. doi:10.1002/adfm.201202433.
- Ohno M et al. (2012) Astaxanthin rich crude extract of Haematococcus pluvialis induces cytochrome P450 1A1 mRNA by activating aryl hydrocarbon receptor in rat hepatoma H4IIE cells. Food Chem 130(2):356–361.
- Ohno M et al. (2012) Sudan III dye strongly induces CYP1A1 mRNA expression in HepG2 cells. J Biochem Mol Toxicol 26(1):16–22.
- Prowse ABJ et al. (2012) Analysis of mitochondrial function and localisation during human embryonic stem cell differentiation in vitro. PLoS ONE 7(12):e52214. doi:10.1371/journal.pone.0052214
- Ranaldi G et al. (2012) Intracellular zinc is required for intestinal cell survival signals triggered by the inflammatory cytokine TNFα. J Nutr Biochem doi:10.1016/j.jnutbio.2012.06.020
- Roberts BLT et al. (2012) Role of disulfide cross-linking of mutant SOD1 in the formation of inclusion-body-like structures. PLoS ONE 7(10):e47838. doi:10.1371/journal.pone.0047838.
- Ramonet D et al. (2012) PARK9-associated ATP13A2 localizes to intracellular acidic vesicles and regulates cation homeostasis and neuronal integrity. Human Mol Gen 21(8):1725–1743.
- Schäfer S et al. (2012) Immunomodulatory influence of bone marrow-derived mesenchymal stem cells on neuroinflammation in astrocyte cultures. J Neuroimmunol 249(1):40–48.
- Sheikholeslam M et al. (2012) Dispersion of multiwalled carbon nanotubes in water using ionic-complementary peptides. Langmuir 28(34):12550–12556.
- Urbanska AM et al. (2012) Therapeutic effect of orally administered microencapsulated oxaliplatin for colorectal cancer. Biomaterials 33(18):4752–4761.
- Van de Vijver E et al. (2012) Defects in Glanzmann thrombasthenia and LAD-III (LAD-1/v) syndrome: the role of integrin β1 and β3 in platelet adhesion to collagen. Blood 119(2):583–586.
- Wang Y et al. (2012) Oxidized phospholipid based pH sensitive micelles for delivery of anthracyclines to resistant leukemia cells in vitro. Int J Pharm 422(1–2):409–417.
- Wang D et al. (2012) Phytochemicals attenuating aberrant activation of β-catenin in cancer cells. PLoS ONE 7(12): e50508. doi:10.1371/journal.pone.0050508
- Weimar CHE et al. (2012) Endometrial stromal cells of women with recurrent miscarriage fail to discriminate between high- and low-quality human embryos. PLoS ONE 7(7):e41424. doi:10.1371/journal.pone.0041424
- Zhan M et al. (2012) The B-MYB transcriptional network guides cell cycle progression and fate decisions to sustain self-renewal and the identity of pluripotent stem cells. PLoS ONE 7(8):e42350. doi:10.1371/journal.pone.0042350
- Curatola AM et al. (2011) Cyclic GMP protects endothelial progenitors from oxidative stress. Angiogenesis 14(3):267–279.
- Hellmann J et al. (2011) Resolvin D1 decreases adipose tissue macrophage accumulation and improves insulin. FASEB J 25:2399-2407.
- Kachadourian R et al. (2011) 2′,5′-Dihydroxychalcone-induced glutathione is mediated by oxidative stress and kinase signaling pathways. Free Radic Biol Med 51(6):1146–1154.
- Krajewska M et al. (2011) Neuronal deletion of caspase 8 protects against brain injury in mouse models of controlled cortical impact and kainic acid-induced excitotoxicty. PLoS ONE 6(9):1–21.
- Lim P et al. (2011) Gap junction-mediated import of microRNA from bone marrow stromal cells can elicit cell cycle quiescence in breast cancer cells. Cancer Res 71:1550–1560.
- Lu C et al. (2011) TLR2 ligand induces protection against cerebral ischemia/reperfusion injury via activation of phosphoinositide 3-kinase/Akt signaling. J Immunol 187(3):1458–1466.
- Eijkelkamp N et al. (2010) Low nociceptor GRK2 prolongs prostaglandin E2 hyperalgesia via biased cAMP signaling to Epac/Rap1, protein kinase Cε, and MEK/ERK. J Neurosci 30(38):12806–12815.
- Smeenk G et al. (2010) The NuRD chromatin–remodeling complex regulates signaling and repair of DNA damage. J Cell Bio 190(5):741–749.
- Wang H et al. (2010) Tissue factor-dependent procoagulant activity of subtilase cytotoxin, a potent AB5 toxin produced by Shiga toxigenic Escherichia coli. J Infect Dis 202(9):1415–1423.
EVOS FL Application Videos
Resources
EVOS FL Software Update
EVOS FL User Manual
EVOS FL Quick Start Guide
EVOS Accessories
Webinars
Cell Analysis Support Center
Find tips, troubleshooting help, and resources for your cell analysis workflow
For Research Use Only. Not for use in diagnostic procedures.
