Solvents for Synthetic and Analytical Chemistry

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Solvents dissolve a solute to form a solution. Mostly liquids, solvents can be divided into either polar or nonpolar based on their dielectric constant.


Polar solvents have one or more electronegative atoms and can be further divided into protic (e.g., water, methanol) and aprotic solvents (e.g., acetone, DMSO) based on the mechanism of solvation. Non-polar solvents (e.g., benzene, hexane) lack partial charges due to the similar electronegativities of the bonding atoms.   

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Solvents Application Guide

Find exactly what you need from our portfolio of more than 800 high-purity solvents formulated to suit applications for LC/MS, HPLC, UHPLC/MS, gas chromatography, spectrometry, and more.

Our solvents are manufactured in ISO 9001-certified facilities and undergo quality assurance testing designed to bring you the lot-to-lot and bottle-to-bottle consistency you rely on.

Webinar: Selecting the Right Solvents for Your Separations

In this webinar, learn about the different grades of reagents, recommendations for their use based on application, and materials and processes to clean and maintain your instruments.