In this webinar Dr. Chris Petucci will provide an overview of how the University of Pennsylvania Metabolomics Core performs targeted and untargeted LC/MS metabolomics for internal and external research investigators and industry. He will also discuss key enabling technologies for in depth understanding of biological pathways in disease and biomarker discovery. Examples of sample preparation, LC/MS method development, and untargeted metabolomics projects in medical research will be presented to illustrate the power of the Thermo Scientific Orbitrap ID-X Tribrid mass spectrometer.
What you will learn:
- Stable and reproducible sample preparation of cells, biological fluids, and tissues for metabolomics
- Essentials of chromatography theory and practice for high resolution chromatography of metabolites
- Strengths of the Orbitrap ID-X LC/MS for untargeted metabolomics
- Basics of statistical data analysis of untargeted metabolomics data using Compound Discoverer software
About the presenter
Chris Petucci Ph.D., Director of the Metabolomics Core, University of Pennsylvania
Chris Petucci received his Ph.D. in analytical chemistry with a focus on mass spectrometry from Purdue University. After his time in drug discovery at Wyeth, he became director of and established a targeted metabolomics core at the Sanford Burnham Prebys Medical Discovery Institute. The Core was a major partner with the Southeast Center for Integrated Metabolomics (SECIM) at the University of Florida, one of six NIH sponsored national centers to spur metabolomics research. He is currently the director of the Penn Metabolomics Core of the Cardiovascular Institute in the Perelman School of Medicine. The Core performs targeted and untargeted metabolomics assays for biomarker discovery to serve internal and external research investigators including industry.