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Estrogen-related receptor gamma (ERRG, ERR3, NR3B3) is an orphan member of the nuclear hormone receptor superfamily. ERRG acts as a transcription activator in the absence of a bound ligand. It binds specifically to an estrogen response element and activates reporter genes controlled by estrogen response elements. ERRG also induces the expression of PERM1 in the skeletal muscle.
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