Plays a role in regulating Notch activity. Plays a role in regulating the expression of CDKN1A and several members of the Wnt pathway, probably via its effects on Notch activity. Required during embryogenesis for inner mass cell survival By similarity. Ota T., Nat. Genet. 36:40-45(2004). The MGC Project Team; Genome Res. 14:2121-2127(2004). Bienvenut W.V.; Submitted (AUG-2005) to UniProtKB.
FLJ10458; Nle; Notchless gene homolog; notchless homolog 1; Notchless protein homolog 1; novel WD40 repeat containing protein