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TAGLN is a transformation and shape-change sensitive actin cross-linking/gelling protein found in fibroblasts and smooth muscle. Its expression is down-regulated in many cell lines, and this down-regulation may be an early and sensitive marker for the onset of transformation. A functional role of this protein is unclear.
22 kDa actin-binding protein; 25 kDa F-actin-binding protein; actin-associated protein p27; DKFZp686B01212; DKFZp686P11128; Protein WS3-10; similar to transgelin; Sm22; sm22 alpha; SM22A; Sm22alpha; SM22-alpha; SMCC; smooth muscle 22 protein; smooth muscle protein 22-alpha; TAGLN; TAGLN1; Transgelin; transgelin variant 2; Ws310; WS3-10
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