beta Arrestin 1 Antibodies

Antibodies that detect beta Arrestin 1 can be used in several scientific applications, including Western Blot, Immunohistochemistry, Immunocytochemistry, Immunoprecipitation and ELISA. These antibodies target beta Arrestin 1 in Human, Mouse, Rat and Non-human primate samples. Our beta Arrestin 1 polyclonal, monoclonal and recombinant monoclonal antibodies are developed in Rabbit and Mouse. These antibodies have been verified by Cell treatment to confirm specificity to beta Arrestin 1. Find the beta Arrestin 1 antibody that fits your needs. Choose from 1 of 26 beta Arrestin 1 antibodies, which have been validated in experiments with 16 publications and ... View more Antibodies that detect beta Arrestin 1 can be used in several scientific applications, including Western Blot, Immunohistochemistry, Immunocytochemistry, Immunoprecipitation and ELISA. These antibodies target beta Arrestin 1 in Human, Mouse, Rat and Non-human primate samples. Our beta Arrestin 1 polyclonal, monoclonal and recombinant monoclonal antibodies are developed in Rabbit and Mouse. These antibodies have been verified by Cell treatment to confirm specificity to beta Arrestin 1. Find the beta Arrestin 1 antibody that fits your needs. Choose from 1 of 26 beta Arrestin 1 antibodies, which have been validated in experiments with 16 publications and 58 images featured in our data gallery.

Browse primary antibodies for WB, Flow, IHC, ICC/IF, ELISA, IP, and other applications. Antibodies with Advanced Verification data have been validated for specificity to ensure that the antibody binds to the antigen stated. If you cannot find the antibody you're looking for, contact us today to develop custom antibodies for specific targets, species and applications.

Target Information

Beta Arrestin 1 is a member of a family of proteins widely expressed but especially abundant in the central nervous system. Serving as an adaptor or scaffold molecule, beta Arrestin 1 is essential for mitogenic signaling and mediates agonist-dependent desensitization and internalization of Gprotein-coupled receptors (GPCRs, e.g., beta 2-adrenergic receptor). After binding to their ligand and interacting with heterotrimeric G proteins, GPCRs are phosphorylated by G-protein receptor kinases (GRKs) on serine residues. Beta Arrestin 1 in the cytosol is phosphorylated by ERK1 and 2 on serine412 in a negative feedback mechanism and binds to the phosphorylated receptors at the plasma membrane. Serine 412 is then dephosphorylated and the GPCRs are internalized, leading to activation of the Ras, Raf, ERK1 and 2 signaling pathway.

Synonyms

1200006I17Rik; ARB1; ARR1; ARRB1; ARRB1 protein; arrdc1; arrestin; arrestin 2; arrestin beta 1; arrestin beta-1; arrestin, beta 1; arrestin-2; AW208571; BARRES; beta-arrestin; beta-arrestin1; beta-arrestin-1; G430100A01Rik; Non-visual arrestin-2

beta Arrestin 1 Antibodies

Target Information

Synonyms

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