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The elongation of primed DNA templates by DNA polymerase delta and DNA polymerase epsilon requires the accessory proteins proliferating cell nuclear antigen (PCNA) and replication factor C (RFC). RFC, also named activator 1, is a protein complex consisting of five distinct subunits of 140, 40, 38, 37, and 36 kDa. This gene encodes the 36 kD subunit. This subunit can interact with the C-terminal region of PCNA. It forms a core complex with the 38 and 40 kDa subunits. The core complex possesses DNA-dependent ATPase activity, which was found to be stimulated by PCNA in an in vitro system. Alternatively spliced transcript variants encoding distinct isoforms have been reported.
2610036A20Rik; A230104O07Rik; AW111824; BB183398; E74 like ETS transcription factor 2; E74-like factor 2; E74-like factor 2 (ets domain transcription factor); E74-like factor 2 (ets domain transcription factor) isoform 1; E74-like factor 2 (ets domain transcription factor) isoform 2; elf2; ets domain transcription factor; ets family transcription factor ELF2A2; ets family transcription factor ELF2C; ETS-related transcription factor Elf-2; EU32; NERF; NERF-1A; NERF-1a,b; NERF-1B; NERF-2; new Ets-related factor
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