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Invitrogen
ELF2 Polyclonal Antibody
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Product Details
PA5-40412
Product Specifications
Species Reactivity
Human,
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Synthetic peptide directed towards the N-terminal of human ELF2 (aa 163-212).
Conjugate
Form
Liquid
Concentration
0.5 mg/mL
Purification
Affinity Chromatography
Storage buffer
PBS with 2% sucrose
Contains
0.09% sodium azide
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Peptide sequence: TSPDSHEPMK KKKVGRKPKT QQSPISNGSP ELGIKKKPRE GKGNTTYLWE
Sequence homology: Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%
Target Information
The elongation of primed DNA templates by DNA polymerase delta and DNA polymerase epsilon requires the accessory proteins proliferating cell nuclear antigen (PCNA) and replication factor C (RFC). RFC, also named activator 1, is a protein complex consisting of five distinct subunits of 140, 40, 38, 37, and 36 kDa. This gene encodes the 36 kD subunit. This subunit can interact with the C-terminal region of PCNA. It forms a core complex with the 38 and 40 kDa subunits. The core complex possesses DNA-dependent ATPase activity, which was found to be stimulated by PCNA in an in vitro system. Alternatively spliced transcript variants encoding distinct isoforms have been reported.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: E74-like factor 2; E74-like factor 2 (ets domain transcription factor); ELF2; ets domain transcription factor; ets family transcription factor ELF2A2; ets family transcription factor ELF2C; ETS-related transcription factor Elf-2; New ETS-related factor
Gene Aliases: 2610036A20Rik; A230104O07Rik; AW111824; BB183398; ELF2; EU32; NERF; NERF-1A; NERF-1a,b; NERF-1B; NERF-2
UniProt ID: (Human) Q15723, (Mouse) Q9JHC9
Entrez Gene ID: (Human) 1998, (Mouse) 69257
transcription, DNA-templated
regulation of transcription from RNA polymerase II promoter
cell differentiation
positive regulation of transcription, DNA-templated
regulation of transcription, DNA-templated
transcription from RNA polymerase II promoter
negative regulation of transcription, DNA-templated
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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