Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
H2B histone family, member N; H2B/n; H2BFH; H2BFN; HIST1H2BO; histone 1, H2bo; Histone H2B type 1-O; Histone H2B.2; Histone H2B.n; Histone H2B2; Histone H2Bn