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The protein encoded by this gene is an isoform of xylosyltransferase, which belongs to a family of glycosyltransferases. This enzyme transfers xylose from UDP-xylose to specific serine residues of the core protein and initiates the biosynthesis of glycosaminoglycan chains in proteoglycans including chondroitin sulfate, heparan sulfate, heparin and dermatan sulfate. The enzyme activity, which is increased in scleroderma patients, is a diagnostic marker for the determination of sclerotic activity in systemic sclerosis.
E030002B02Rik; Peptide O-xylosyltransferase 1; peptide O-xylosyltransferase 2; protein xylosyltransferase; protein xylosyltransferase 2; PXYLT2; SOS; UDP-D-xylose:proteoglycan core protein beta-D-xylosyltransferase; UNQ3058/PRO9878; XT2; XT-II; Xylosyltransferase 2; xylosyltransferase II; Xylt2; xylt-II
100 µL
100 µL
100 µL
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