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Proteintech
DDX39A Polyclonal Antibody
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Product Details
11723-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Published species
Chicken,
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
DDX39A Fusion Protein Ag2311 (1-322 aa encoded by BC032128)
Conjugate
Form
Liquid
Concentration
0.27 mg/mL
Amount
40.5 µg
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
This antibody may cross-react with DDX39B.
Immunogen sequence: MAEQDVEND LLDYDEEEEP QAPQESTPAP PKKDIKGSYV SIHSSGFRDF LLKPELLRAI VDCGFEHPSE VQHECIPQAI LGMDVLCQAK SGMGKTAVFV LATLQQIEPV NGQVTVLVMC HTRELAFQIS KEYERFSKYM PSVKVSVFFG GLSIKKDEEV LKKNCPHVVV GTPGRILALV RNRSFSLKNV KHFVLDECDK MLEQLDMRRD VQEIFRLTPH EKQCMMFSAT LSKDIRPVCR KFMQDPMEVF VDDETKLTLH GLQQYYVKLK DSEKNRKLFD LLDVLEFNQP VTLSAVQGFP AADPGGHQSV WPGDGHRASQ HRL (1-322 aa encoded by BC032128)
Target Information
This gene encodes a member of the DEAD box protein family. These proteins are characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD) and are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure, such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution patterns, some members of the DEAD box protein family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. This gene is thought to play a role in the prognosis of patients with gastrointestinal stromal tumors. A pseudogene of this gene is present on chromosome 13. Alternate splicing results in multiple transcript variants. Additional alternatively spliced transcript variants of this gene have been described, but their full-length nature is not known.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: ATP-dependent RNA helicase DDX39; ATP-dependent RNA helicase DDX39A; DEAD (Asp-Glu-Ala-Asp) box polypeptide 39; DEAD (Asp-Glu-Ala-Asp) box polypeptide 39A; DEAD box protein 39; DEAD-box helicase 39A; DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 39; Nuclear RNA helicase URH49; Nuclear RNA helicase, DECD variant of DEAD box family; UAP56-related helicase, 49 kDa; unnamed protein product
Gene Aliases: 2610307C23Rik; BAT1; BAT1L; DDX39; DDX39A; DDXL; URH49
UniProt ID: (Human) O00148, (Mouse) Q8VDW0, (Rat) Q5U216
Entrez Gene ID: (Human) 10212, (Mouse) 68278, (Rat) 89827
mRNA splicing, via spliceosome
mRNA export from nucleus
mRNA processing
cellular response to DNA damage stimulus
RNA splicing
regulation of gene expression
RNA secondary structure unwinding
toll-like receptor signaling pathway
cytoplasmic pattern recognition receptor signaling pathway
RNA export from nucleus
negative regulation of innate immune response
negative regulation of RNA export from nucleus
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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