Immunoprecipitation analysis of UQCRC1 using a UQCRC1 Monoclonal antibody (Product # 45-7125). Each lane was immunoprecipitated using the UQCRC1 Monoclonal antibody (Product # 45-7125) at a concentration of 10 µg/mg of lysate. Lane 1: 0.1mg of Bovine mitochondria, Lane 2: 0.05mg Bovine mitochondria, Lane 3: 0.05mg Human mitochondria.

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Product Details

45-7125

Applications

Tested Dilution

Publications

Immunoprecipitation (IP)

Assay-dependent

Product Specifications

Species Reactivity

Bovine, Human, Mouse, Rat

Host/Isotype

Mouse / IgG1, kappa

Class

Monoclonal

Type

Antibody

Clone

11A51H12

Immunogen

Bovine Heart Complex III

Conjugate

Agarose Agarose Agarose

Form

Liquid

250 µg

Purification

Ammonium sulfate precipitation

Storage buffer

HEPES buffered saline

Contains

0.02% sodium azide

Storage conditions

4°C, do not freeze

Shipping conditions

Ambient (domestic); Wet ice (international)

AB_2533828

Target Information

Complex III, or ubiquinol cytochrome c oxidoreductase, is a complex of 11 subunits and catalyses electron transfer from reduced ubiquinone or coenzyme Q 10 to cytochrome c. The complex contains 11 different subunits, one of which, cytochrome b, is encoded on mitochondrial DNA, while the remainder subunits are nuclear-encoded. Genetic complex III deficiencies occur but are rare.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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Bioinformatics

Protein Aliases: Complex III subunit 1; Complex III subunit 10; Complex III subunit 2; Complex III subunit 4; Complex III subunit 5; Complex III subunit 6; Complex III subunit 7; Complex III subunit 8; Complex III subunit 9; Complex III subunit IV; Complex III subunit VII; Complex III subunit VIII; Complex III subunit X; Complex III subunit XI; Core protein I; Core protein II; core protein II precursor; CYC1; Cytochrome b-c1 complex subunit 1, mitochondrial; Cytochrome b-c1 complex subunit 10; Cytochrome b-c1 complex subunit 2, mitochondrial; Cytochrome b-c1 complex subunit 4; Cytochrome b-c1 complex subunit 5; Cytochrome b-c1 complex subunit 6, mitochondrial; Cytochrome b-c1 complex subunit 7; Cytochrome b-c1 complex subunit 8; Cytochrome b-c1 complex subunit 9; Cytochrome b-c1 complex subunit Rieske, mitochondrial; cytochrome bc-1 complex core protein II; Cytochrome c-1; cytochrome c1; Cytochrome c1 non-heme 11 kDa protein; Cytochrome c1 non-heme 7 kDa protein; Cytochrome c1, heme protein, mitochondrial; cytochrome C1, nonheme 11 kDa protein; cytochrome C1, nonheme 7kDa protein; epididymis secretory sperm binding protein; Liver regeneration-related protein LRRGT00195; Low molecular mass ubiquinone-binding protein; low molecular mass ubiquinone-binding protein (9.5kD); low molecular mass ubiquinone-binding protein (Qpc-pending); Mitochondrial hinge protein; mitochondrial hinge protein precursor; mitochondrial ubiquinone-binding protein; QP-C; Rieske iron-sulfur protein; Rieske iron-sulfur protein precursor; Rieske protein UQCRFS1; RISP; ubiquinol cytochrome c reductase hinge protein; ubiquinol-cytochrome c reductase (6.4kD) subunit; ubiquinol-cytochrome c reductase binding protein; ubiquinol-cytochrome c reductase binding protein-like; ubiquinol-cytochrome c reductase complex (7.2 kD); Ubiquinol-cytochrome c reductase complex 11 kDa protein; Ubiquinol-cytochrome c reductase complex 14 kDa protein; Ubiquinol-cytochrome c reductase complex 6.4 kDa protein; Ubiquinol-cytochrome c reductase complex 7.2 kDa protein; ubiquinol-cytochrome c reductase complex 7.2kDa protein; Ubiquinol-cytochrome c reductase complex 9.5 kDa protein; ubiquinol-cytochrome C reductase complex core protein 2, mitochondrial precursor (Complex III subunit II); ubiquinol-cytochrome c reductase complex protein; Ubiquinol-cytochrome c reductase complex ubiquinone-binding protein QP-C; ubiquinol-cytochrome c reductase core protein 1; ubiquinol-cytochrome c reductase core protein I; ubiquinol-cytochrome c reductase core protein II; Ubiquinol-cytochrome c reductase iron-sulfur subunit; ubiquinol-cytochrome c reductase subunit; ubiquinol-cytochrome c reductase, 6.4kDa subunit; ubiquinol-cytochrome c reductase, complex III subunit VI; ubiquinol-cytochrome c reductase, complex III subunit VII, 9.5kDa; ubiquinol-cytochrome c reductase, complex III subunit VIII; ubiquinol-cytochrome c reductase, complex III subunit X, 7.2kDa; ubiquinol-cytochrome c reductase, complex III subunit XI; Ubiquinol-cytochrome-c reductase complex core protein 1; Ubiquinol-cytochrome-c reductase complex core protein 2; Ubiquinol-cytochrome-c reductase complex cytochrome c1 subunit; ubiquinone-binding protein; ubiquinone-binding protein precursor; UCRC; unnamed protein product; UQCRB

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Gene Aliases: 0710008D09Rik; 1100001F06Rik; 1110020P15Rik; 1110032G10Rik; 1500004O06Rik; 1500040F11Rik; 2210415M14Rik; 2210416J04Rik; 2310021J10Rik; 2610002H19Rik; 2610041P16Rik; 4430402G14Rik; 5830407L17Rik; 9.5kDa; AA408921; AA959903; AA960494; AI875505; AL022707; c1502; CYC1; D3S3191; HSPC051; HSPC119; HSPC151; LRRGT00195; MC3DN10; MC3DN11; MC3DN3; MC3DN4; MC3DN5; MC3DN6; PKNPY; QCR1; QCR10; QCR2; QCR6; QCR7; QCR8; QCR9; QP-C; QPC; RIP1; RIS1; RISP; UCCR7.2; UCRC; UQBC; UQBP; UQCR; UQCR1; UQCR10; UQCR11; UQCR2; UQCR4; UQCR5; UQCR6; UQCR7; UQCR8; UQCRB; Uqcrbl; UQCRC1; UQCRC2; UQCRFS1; UQCRH; UQCRQ; UQPC

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Function(s)

heme binding metal ion binding protein binding ubiquinol-cytochrome-c reductase activity electron carrier activity molecular_function iron ion binding ubiquitin protein ligase binding macromolecular complex binding catalytic activity metalloendopeptidase activity 2 iron, 2 sulfur cluster binding oxidoreductase activity iron-sulfur cluster binding protein complex binding oxidoreductase activity, acting on diphenols and related substances as donors reductase oxidoreductase metabolite interconversion enzyme metalloprotease

Process(es)

mitochondrial electron transport, ubiquinol to cytochrome c response to glucagon cellular respiration hydrogen ion transmembrane transport transport oxidation-reduction process electron transport chain generation of precursor metabolites and energy oxidative phosphorylation aerobic respiration response to activity response to alkaloid proteolysis respiratory electron transport chain mitochondrial respiratory chain complex III assembly subthalamus development pons development cerebellar Purkinje cell layer development hippocampus development thalamus development hypothalamus development pyramidal neuron development midbrain development biological_process protein heterooligomerization response to hormone response to drug response to antibiotic

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If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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Complex III Monoclonal Antibody (11A51H12), Agarose

Complex III Antibody (45-7125) in IP