Immunoprecipitation analysis of UQCRC1 using a UQCRC1 Monoclonal antibody (Product # 45-7125). Each lane was immunoprecipitated using the UQCRC1 Monoclonal antibody (Product # 45-7125) at a concentration of 10 µg/mg of lysate. Lane 1: 0.1mg of Bovine mitochondria, Lane 2: 0.05mg Bovine mitochondria, Lane 3: 0.05mg Human mitochondria.

Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.

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Product Details

45-7125

Applications

Tested Dilution

Publications

Immunoprecipitation (IP)

Assay-dependent

Product Specifications

Species Reactivity

Bovine, Human, Mouse, Rat

Host/Isotype

Mouse / IgG1, kappa

Class

Monoclonal

Type

Antibody

Clone

11A51H12

Immunogen

Bovine Heart Complex III

Conjugate

Agarose Agarose Agarose

Form

Liquid

250 µg

Purification

Ammonium sulfate precipitation

Storage buffer

HEPES buffered saline

Contains

0.02% sodium azide

Storage conditions

4°C, do not freeze

Ambient (domestic); Wet ice (international)

AB_2533828

Target Information

Complex III, or ubiquinol cytochrome c oxidoreductase, is a complex of 11 subunits and catalyses electron transfer from reduced ubiquinone or coenzyme Q 10 to cytochrome c. The complex contains 11 different subunits, one of which, cytochrome b, is encoded on mitochondrial DNA, while the remainder subunits are nuclear-encoded. Genetic complex III deficiencies occur but are rare.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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Bioinformatics

Protein Aliases: complex III subunit 1; complex III subunit 10; complex III subunit 2; complex III subunit 4; complex III subunit 5; complex III subunit 6; complex III subunit 7; complex III subunit 8; Complex III subunit 9; complex III subunit IV; complex III subunit VII; complex III subunit VIII; complex III subunit X; complex III subunit XI; core protein I; core protein II; core protein II precursor; CYC1; cytochrome b-c1 complex subunit 10; cytochrome b-c1 complex subunit 4; cytochrome b-c1 complex subunit 5; cytochrome bc-1 complex core protein II; cytochrome c-1; cytochrome c1; cytochrome c1 non-heme 11 kDa protein; cytochrome c1 non-heme 7 kDa protein; cytochrome C1, nonheme 11 kDa protein; cytochrome C1, nonheme 7kDa protein; epididymis secretory sperm binding protein; liver regeneration-related protein LRRGT00195; low molecular mass ubiquinone-binding protein; low molecular mass ubiquinone-binding protein (9.5kD); low molecular mass ubiquinone-binding protein (Qpc-pending); mitochondrial hinge protein; mitochondrial hinge protein precursor; mitochondrial ubiquinone-binding protein; putative ubiquinol-cytochrome c reductase binding protein; QP-C; Rieske iron-sulfur protein; Rieske iron-sulfur protein precursor; Rieske protein UQCRFS1; RISP; Subunit 9; ubiquinol-cytochrome c reductase (6.4kD) subunit; ubiquinol-cytochrome c reductase binding protein; ubiquinol-cytochrome c reductase complex (7.2 kD); ubiquinol-cytochrome c reductase complex 11 kDa protein; ubiquinol-cytochrome c reductase complex 14 kDa protein; ubiquinol-cytochrome c reductase complex 6.4 kDa protein; ubiquinol-cytochrome c reductase complex 7.2 kDa protein; ubiquinol-cytochrome c reductase complex 9.5 kDa protein; ubiquinol-cytochrome C reductase complex core protein 2, mitochondrial precursor (Complex III subunit II); ubiquinol-cytochrome c reductase complex protein; ubiquinol-cytochrome c reductase complex ubiquinone-binding protein QP-C; ubiquinol-cytochrome c reductase core protein I; ubiquinol-cytochrome c reductase core protein II; ubiquinol-cytochrome c reductase iron-sulfur subunit; ubiquinol-cytochrome c reductase subunit; ubiquinol-cytochrome c reductase, 6.4kDa subunit; ubiquinol-cytochrome c reductase, complex III subunit VI; ubiquinol-cytochrome c reductase, complex III subunit VII, 9.5kDa; ubiquinol-cytochrome c reductase, complex III subunit VIII; ubiquinol-cytochrome c reductase, complex III subunit X, 7.2kDa; ubiquinol-cytochrome-c reductase complex core protein 1; ubiquinol-cytochrome-c reductase complex core protein 2; ubiquinol-cytochrome-c reductase complex cytochrome c1 subunit; ubiquinone-binding protein; ubiquinone-binding protein precursor; UCRC; unnamed protein product; UQCRB

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Gene Aliases: 0710008D09Rik; 1100001F06Rik; 1110020P15Rik; 1110032G10Rik; 1500004O06Rik; 1500040F11Rik; 2210415M14Rik; 2210416J04Rik; 2310021J10Rik; 2610002H19Rik; 2610041P16Rik; 4430402G14Rik; 5830407L17Rik; 9.5kDa; c1502; Cyct1; D3S3191; HSPC051; HSPC119; HSPC151; ISP; LRRGT00195; MC3DN10; MC3DN11; MC3DN3; MC3DN4; MC3DN5; MC3DN6; PKNPY; QCR1; QCR10; QCR2; QCR6; QCR7; QCR8; QCR9; QP-C; QPC; RIP1; RIS1; RISP; UCCR7.2; UCRC; UQBC; UQBP; UQCR; UQCR1; UQCR2; UQCR4; UQCR5; UQCR6; UQCR7; UQCR8; Uqcrb; Uqcrbl; UQPC

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Function(s)

heme binding metal ion binding protein binding ubiquinol-cytochrome-c reductase activity electron carrier activity ubiquitin protein ligase binding macromolecular complex binding catalytic activity metalloendopeptidase activity 2 iron, 2 sulfur cluster binding oxidoreductase activity metalloprotease reductase oxidoreductase metabolite interconversion enzyme

Process(es)

mitochondrial electron transport, ubiquinol to cytochrome c response to glucagon cellular respiration hydrogen ion transmembrane transport electron transport chain generation of precursor metabolites and energy oxidative phosphorylation aerobic respiration response to activity response to alkaloid protein localization to mitochondrion oxidation-reduction process proteolysis respiratory electron transport chain mitochondrial respiratory chain complex III assembly subthalamus development pons development cerebellar Purkinje cell layer development hippocampus development thalamus development hypothalamus development pyramidal neuron development midbrain development response to xenobiotic stimulus response to hormone biological_process

Performance Guarantee

If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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Complex III Monoclonal Antibody (11A51H12), Agarose

Complex III Antibody (45-7125) in IP