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Proteintech
CBX3 Monoclonal Antibody (1A5A3)
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Product Details
66446-1-IG
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse
Host/Isotype
Mouse
/ IgG2a
Class
Monoclonal
Type
Antibody
Clone
1A5A3
Immunogen
CBX3 Fusion Protein Ag19112 (1-183 aa encoded by BC000954)
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Protein A
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
Immunogen sequence: MASNKTTLQ KMGKKQNGKS KKVEEAEPEE FVVEKVLDRR VVNGKVEYFL KWKGFTDADN TWEPEENLDC PELIEAFLNS QKAGKEKDGT KRKSLSDSES DDSKSKKKRD AADKPRGFAR GLDPERIIGA TDSSGELMFL MKWKDSDEAD LVLAKEANMK CPQIVIAFYE ERLTWHSCPE DEAQ (1-183 aa encoded by BC000954)
Target Information
At the nuclear envelope, the nuclear lamina and heterochromatin are adjacent to the inner nuclear membrane. The protein encoded by this gene binds DNA and is a component of heterochromatin. This protein also can bind lamin B receptor, an integral membrane protein found in the inner nuclear membrane. The dual binding functions of the encoded protein may explain the association of heterochromatin with the inner nuclear membrane.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: chromobox homolog 3; chromobox homolog 3 (HP1 gamma homolog, Drosophila); Chromobox protein homolog 3; HECH; heterochromatin protein 1 gamma; Heterochromatin protein 1 homolog gamma; heterochromatin protein HP1 gamma; heterochromatin-like protein 1; HGNC:1553; HP1 gamma; HP1 gamma homolog; HPy; Modifier 2 protein; OTTHUMP00000202463
Gene Aliases: CBX3; HECH; HP1-GAMMA; HP1g; HP1gamma; HP1Hs-gamma; M32
UniProt ID: (Human) Q13185
Entrez Gene ID: (Human) 11335, (Mouse) 12417
chromatin organization
chromatin remodeling
cellular response to DNA damage stimulus
heterochromatin assembly
negative regulation of transcription, DNA-templated
rhythmic process
cellular response to dexamethasone stimulus
transcription, DNA-templated
regulation of transcription, DNA-templated
chromatin modification
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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