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Proteintech
FRZB Monoclonal Antibody (2B4A1)
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Product Details
67081-1-IG
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse
Host/Isotype
Mouse
/ IgG1
Class
Monoclonal
Type
Antibody
Clone
2B4A1
Immunogen
FRZB Fusion Protein Ag28147
Conjugate
Form
Liquid
Concentration
1000 µg/mL
Amount
150 µg
Purification
Protein G
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice
Product Specific Information
Aliquoting is unnecessary for -20°C storage.
Target Information
The protein encoded by this gene is a secreted protein that is involved in the regulation of bone development. Defects in this gene are a cause of female-specific osteoarthritis (OA) susceptibility.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: FREOS1; Frezzled; Fritz; frizzled homolog-related; Frizzled-related protein 1; FrzB-1; FRZB1sFRP-3; Secreted frizzled-related protein 3; secreted frizzled-related sequence protein 3; sFRP-3; SFRP3frezzled; unnamed protein product
Gene Aliases: FIZ; FRE; frezzled; FRITZ; FRP; FRP-3; FRZB; FRZB-1; FRZB-PEN; FRZB1; FZRB; hFIZ; OS1; SFRP3; SRFP3
UniProt ID: (Human) Q92765, (Mouse) P97401
Entrez Gene ID: (Human) 2487, (Mouse) 20378
skeletal system development
epithelial cell development
negative regulation of cell proliferation
negative regulation of cell development
neural crest cell differentiation
Wnt signaling pathway
cell differentiation
negative regulation of Wnt signaling pathway
negative regulation of cell growth
non-canonical Wnt signaling pathway
inner ear morphogenesis
positive regulation of apoptotic process
regulation of cell differentiation
positive regulation of fat cell differentiation
convergent extension involved in organogenesis
canonical Wnt signaling pathway
negative regulation of cartilage development
somite development
hepatocyte differentiation
negative regulation of hepatocyte differentiation
negative regulation of canonical Wnt signaling pathway
cochlea morphogenesis
multicellular organism development
Disclaimer
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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