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Proteintech
SAR1B Monoclonal Antibody (1B11A1)
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Product Details
67765-1-IG
Product Specifications
Species Reactivity
Human,
Mouse,
Pig,
Rabbit,
Rat
Host/Isotype
Mouse
/ IgG1
Class
Monoclonal
Type
Antibody
Clone
1B11A1
Immunogen
SAR1B Fusion Protein Ag7718
Conjugate
Form
Liquid
Concentration
1000 µg/mL
Amount
150 µg
Purification
Protein G
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice
Product Specific Information
Aliquoting is unnecessary for -20°C storage.
Target Information
The protein encoded by this gene is a small GTPase that acts as a homodimer. The encoded protein is activated by the guanine nucleotide exchange factor PREB and is involved in protein transport from the endoplasmic reticulum to the Golgi. This protein is part of the COPII coat complex. Defects in this gene are a cause of chylomicron retention disease (CMRD), also known as Anderson disease (ANDD). Two transcript variants encoding the same protein have been found for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: 2310075M17Rik; GTBPB; GTP-binding protein B; GTP-binding protein SAR1b; GTP-binding protein Sara; GTPBP; SAR1 gene homolog B; SAR1 homolog B; SAR1a gene homolog 2; SAR1b gene homolog; Secretion-associated Ras-related GTPase 1B; Small COPII coat GTPase SAR1B; small GTP binding protein; unnamed protein product
Gene Aliases: 2310075M17Rik; 2900019I22Rik; ANDD; CMRD; GTBPB; SAR1B; SARA1B; SARA2; SARB
UniProt ID: (Human) Q9Y6B6, (Pig) Q5PYH3, (Rat) Q5HZY2, (Mouse) Q9CQC9
Entrez Gene ID: (Human) 51128, (Rabbit) 100340384, (Pig) 494017, (Rat) 287276, (Mouse) 66397
antigen processing and presentation of peptide antigen via MHC class I
regulation of COPII vesicle coating
intracellular protein transport
ER to Golgi vesicle-mediated transport
protein transport
vesicle organization
vesicle-mediated transport
regulation of lipid transport
lipoprotein transport
COPII vesicle coating
lipid homeostasis
membrane organization
cargo loading into COPII-coated vesicle
lipid export from cell
regulation of TORC1 signaling
negative regulation of TORC1 signaling
cellular response to leucine starvation
biological_process
transport
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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