Immunogen sequence: MDEEGYLYVMS RVDDVINVAG HRISAGAIEE SILSHGTVAD CAVVGKEDPL KGHVPLALCV LRKDINATEE QVLEEIVKHV RQNIGPVAAF RNAVFVK
Highest antigen sequence identity to the following orthologs - mouse 95%, rat 95%.
Catalyzes the synthesis of acetyl-CoA from short-chain fatty acids (PubMed:28003429). Propionate is the preferred substrate (PubMed:28003429). Can utilize acetate and butyrate with a much lower affinity. [UniProt]
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Acetate--CoA ligase 3; Acyl-CoA synthetase short-chain family member 3; Acyl-CoA synthetase short-chain family member 3, mitochondrial; AMP-binding enzyme, 33217; Propionate--CoA ligase
Gene Aliases: ACSS3
UniProt ID: (Human) Q9H6R3
Entrez Gene ID: (Human) 79611
Molecular Function: ligase