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Product Details
PA5-103353
| Applications | Tested Dilution | Publications |
|---|---|---|
Western Blot (WB) |
1:1,000-1:3,000 | - |
| Product Specifications | |
|---|---|
Species Reactivity |
Human |
Host/Isotype |
Rabbit / IgG |
Class |
Polyclonal |
Type |
Antibody |
Immunogen |
A synthesized peptide derived from human AKAP9, corresponding to a region within C-terminal amino acids. |
Conjugate |
Unconjugated |
Form |
Liquid |
Concentration |
1 mg/mL |
Purification |
Affinity chromatography |
Storage buffer |
PBS, pH 7.4, with 50% glycerol |
Contains |
0.02% sodium azide |
Storage conditions |
-20°C |
RRID |
AB_2852698 |
Target Information
The A-kinase anchor proteins are a group of structurally diverse proteins which have the common function of binding to the regulatory subunit of protein kinase A and confining the holoenzyme to discrete locations within the cell. This gene encodes a member of the AKAP family. Alternate splicing of this gene results in at least two isoforms that localize to the centrosome and the Golgi apparatus, and interact with numerous signaling proteins from multiple signal transduction pathways. These signaling proteins include type II protein kinase A, serine/threonine kinase protein kinase N, protein phosphatase 1, protein phosphatase 2a, protein kinase C-epsilon and phosphodiesterase 4D3.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: A kinase (PRKA) anchor protein (yotiao) 9; A kinase (PRKA) anchor protein 9; A-kinase anchor protein 350 kDa; A-kinase anchor protein 450 kDa; A-kinase anchor protein 9; AKAP 120-like protein; AKAP 350; AKAP 450; AKAP-9; AKAP9-BRAF fusion protein; Centrosome- and Golgi-localized PKN-associated protein; centrosome- and golgi-localized protein kinase N-associated protein; CG-NAP; kinase N-associated protein; PRKA9; Protein hyperion; protein kinase A anchoring protein 9; Protein kinase A-anchoring protein 9; protein phosphatase 1, regulatory subunit 45; Protein yotiao
Gene Aliases: AKAP-9; AKAP350; AKAP450; AKAP9; CG-NAP; HYPERION; KIAA0803; LQT11; MU-RMS-40.16A; PPP1R45; PRKA9; YOTIAO
UniProt ID: (Human) Q99996
Entrez Gene ID: (Human) 10142
G2/M transition of mitotic cell cycle
MAPK cascade
transport
microtubule nucleation
signal transduction
chemical synaptic transmission
positive regulation of peptidyl-serine phosphorylation
positive regulation of GTPase activity
regulation of membrane repolarization
regulation of ventricular cardiac muscle cell membrane repolarization
cardiac conduction
cellular response to cAMP
regulation of heart rate by cardiac conduction
positive regulation of potassium ion transmembrane transporter activity
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