Invitrogen

ALOX15 Polyclonal Antibody

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ALOX15 Antibody in Immunohistochemistry (Paraffin) (IHC (P)) — Immunohistochemical analysis of ALOX15 in Human Skeletal Muscle using a ALOX15 monoclonal antibody (Product #PA5-19052) at 2 µg/mL. The Human Skeletal Muscle tissue section was paraffin embeded and detected using steamed antigen retrieval with citrate buffer pH 6, AP-staining.

ALOX15 Antibody in Western Blot (WB) — Western Blot staining of nuclear HeLa cell lysate using Product # PA5-19052 at a concentration of 0.2 µg/mL, the primary antibody incubation was 1 hour and the detection method was chemiluminescence.

Product Details

PA5-19052

Applications	Tested Dilution	Publications
Western Blot (WB)	0.2-0.5 µg/mL	-
Immunohistochemistry (IHC)	2 µg/mL	-

Product Specifications
Species Reactivity	Human
Host/Isotype	Goat / IgG
Class	Polyclonal
Type	Antibody
Immunogen	Synthetic peptide sequence (HYKTDVAVKDDPE) corresponding to the internal amino acids of ALOX15 View immunogen
Conjugate	Unconjugated
Form	Liquid
Concentration	0.5 mg/mL
Purification	Antigen affinity chromatography
Storage buffer	TBS, pH 7.3, with 0.5% BSA
Contains	0.02% sodium azide
Storage conditions	-20° C, Avoid Freeze/Thaw Cycles
RRID	AB_10985497

Target Information

ALOX15 converts arachidonic acid to 15S-hydroperoxyeicosatetraenoic acid. The protein also acts on C-12 of arachidonate as well as on linoleic acid.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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Bioinformatics

Protein Aliases: 12-LOX; 12/15-lipoxygenase; 15-lipooxygenase-1; 15-LOX; 15-LOX2; Arachidonate 12-lipoxygenase, leukocyte-type; Arachidonate 15-lipoxygenase; Arachidonate omega-6 lipoxygenase; Hepoxilin A3 synthase Alox15; Linoleate 13S-lipoxygenase; Polyunsaturated fatty acid lipoxygenase ALOX15

Gene Aliases: 12-LOX; 15-LOX-1; 15LOX-1; ALOX15; LOG15

UniProt ID: (Human) P16050

Entrez Gene ID: (Human) 246

Molecular Function: oxygenase

Function(s)

ossification negative regulation of adaptive immune response phosphatidylethanolamine biosynthetic process leukotriene metabolic process inflammatory response positive regulation of cell-substrate adhesion arachidonic acid metabolic process lipoxygenase pathway bone mineralization positive regulation of actin filament polymerization positive regulation of heterotypic cell-cell adhesion response to endoplasmic reticulum stress regulation of peroxisome proliferator activated receptor signaling pathway cellular response to interleukin-13 wound healing apoptotic cell clearance hepoxilin biosynthetic process oxidation-reduction process positive regulation of ERK1 and ERK2 cascade cellular response to calcium ion regulation of engulfment of apoptotic cell lipoxin A4 biosynthetic process

Process(es)

arachidonate 12-lipoxygenase activity iron ion binding protein binding phosphatidylinositol-4,5-bisphosphate binding hepoxilin-epoxide hydrolase activity arachidonate 15-lipoxygenase activity hepoxilin A3 synthase activity eoxin A4 synthase activity

ALOX15 Polyclonal Antibody

Product Details

PA5-19052

Western Blot (WB)

Immunohistochemistry (IHC)

Species Reactivity

Host/Isotype

Class

Type

Immunogen

Conjugate

Form

Concentration

Purification

Storage buffer

Contains

Storage conditions

RRID

Target Information

References (0)

Bioinformatics

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