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Product Details
CL488-23479
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
AMH fusion protein Ag20166
Conjugate
Excitation/Emission Max
493/522 nm
Form
Liquid
Concentration
1 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol, 0.5% BSA
Contains
0.05% ProClin 300
Storage conditions
-20° C, store in dark
Shipping conditions
Wet ice
Product Specific Information
Immunogen sequence: MRDLPLTSL ALVLSALGAL LGTEALRAEE PAVGTSGLIF REDLDWPPGS PQEPLCLVAL GGDSNGSSSP LRVVGALSAY EQAFLGAVQR ARWGPRDLAT FGVCNTGDRQ AALPSLRRLG AWLRDPGGQR LVVLHLEEVT WEPTPSLRFQ EPPPGGAGPP ELALLVLYPG PGPEVTVTRA GLPGAQSLCP SRDTRYLVLA VDRPAGAWRG SGLALTLQPR GEDSRLSTAR LQALLFGDDH RCFTRMTPAL LLLPRSEPAP LPAHGQLDTV PFPPPRPSAE LEESPPSADP FLETLTRLVR ALRVPPARAS APRLALDPDA LAGFPQGLVN LSDPAALERL LDGEEPLLLL LRPTAATTGD PAPLHDPTSA PWATALARRV AAELQAAAAE LRSLPGLPPA TAPLLARLLA LCPGGPGGLG DPLRALLLLK ALQGLRVEWR GRDPRGPGRA QRSAGATAAD GPCALRELSV DLRAERSVLI PETYQANNCQ GVCGWPQSDR NPRYGNHVVL LLKMQARGAA LARPPCCVPT AYAGKLLISL SEERISAHHV PNMVATECGC R
Target Information
Anti mullerian hormone (AMH) is a member of the TGF beta superfamily. It is secreted as a homodimeric 140 kDa disulfide linked precursor that is cleaved to release the mature 30 kDa homodimer. Originally classified as a fetal testicular hormone that inhibits Mullerian duct development, AMH is expressed post natally by immature Sertoli cells, and to a lesser degree by granulosa cells. AMH plays a role in testicular differentiation and in the regulation of ovarian follicle growth.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: AMH; Anti - Mullerian hormone (Mulerian inhibiting substance); Anti-Muellerian hormone; MIS; Muellerian-inhibiting factor; Muellerian-inhibiting substance; Mullerian inhibiting factor; Mullerian inhibiting substance
Gene Aliases: AMH; MIF; MIS
UniProt ID: (Human) P03971, (Rat) P49000, (Mouse) P27106
Entrez Gene ID: (Human) 268, (Rat) 25378, (Mouse) 11705
preantral ovarian follicle growth
urogenital system development
Mullerian duct regression
cell-cell signaling
gonadal mesoderm development
aging
positive regulation of gene expression
response to organic cyclic compound
response to drug
positive regulation of NF-kappaB transcription factor activity
negative regulation of ovarian follicle development
sex determination
sex differentiation
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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