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Invitrogen
BBS7 Polyclonal Antibody
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Product Details
PA5-37952
Product Specifications
Species Reactivity
Human,
Rat
Host/Isotype
Goat
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Peptide with sequence HCILEEADHLQE, from the internal region of BBS7 (aa 647-658).
Conjugate
Form
Liquid
Concentration
0.5 mg/mL
Amount
100 µg
Purification
Ammonium sulfate precipitation
Storage buffer
TBS, pH 7.3, with 0.5% BSA
Contains
0.02% sodium azide
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
This antibody is predicted to react with mouse, dog and cow based on sequence homology.
This antibody is tested in Peptide ELISA: antibody detection limit dilution 128,000.
Target Information
BBS7, also named as BBS2L1, is a component of the BBSome complex which is required for ciliogenesis but is dispensable for centriolar satellite function. BBS7 is mediated in part by the Rab8 GDP/GTP exchange factor, which localizes to the basal body and contacts the BBSome.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Bardet-Biedl syndrome 7 protein; BBS2-like 1; BBS2-like protein 1; BBSome complex member BBS7; FLJ10715; unnamed protein product
Gene Aliases: BBS2L1; BBS7
UniProt ID: (Human) Q8IWZ6
Entrez Gene ID: (Human) 55212, (Rat) 361930
eye development
regulation of transcription from RNA polymerase II promoter
smoothened signaling pathway
brain development
heart development
protein localization
biological_process
positive regulation of proteasomal ubiquitin-dependent protein catabolic process
nonmotile primary cilium assembly
fat cell differentiation
palate development
limb development
heart looping
determination of left/right symmetry
visual perception
protein transport
cell projection organization
melanosome transport
intracellular transport
digestive tract morphogenesis
pigment granule aggregation in cell center
cilium morphogenesis
primary palate development
non-motile cilium assembly
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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