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BRCA2 Polyclonal Antibody

View all (22) BRCA2 antibodies

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BRCA2 Polyclonal Antibody

Product Details

BS-1210R

Applications
Tested Dilution
Publications

Western Blot (WB)

1:200
-

Immunohistochemistry (Paraffin) (IHC (P))

1:200
-

Immunohistochemistry (Frozen) (IHC (F))

1:100-1:500
-

Immunocytochemistry (ICC/IF)

1:50-1:200
-

ELISA (ELISA)

1:500-1:1,000
-
Product Specifications

Species Reactivity

Human, Mouse, Rat

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

KLH conjugated synthetic peptide derived from human BRCA2, amino acids 21-130.
3D Epitope / Immunogen

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

1 mg/mL

Amount

100 µg

Purification

Protein A

Storage buffer

0.01M TBS, pH 7.4, with 50% glycerol, 1% BSA

Contains

0.02% ProClin 300

Storage conditions

-20°C

Shipping conditions

Ambient (domestic); Wet ice (international)

Target Information

Breast Cancer Type 2 susceptibility protein (BRCA2) is a tumor-suppressor protein reported to be involved in double-strand break repair, homologous recombination and S-phase checkpoint activation.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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Bioinformatics

Protein Aliases: brca 2; brca-2; BRCA1/BRCA2-containing complex, subunit 2; BRCA2 DNA repair associated protein; breast and ovarian cancer susceptibility gene, early onset; breast and ovarian cancer susceptibility protein 2; breast cancer 2 tumor suppressor; breast cancer 2, early onset; breast cancer 2, mutation 1, University of Wisconsin-Madison; breast cancer susceptibility protein 2; Breast cancer type 2 susceptibility protein; Breast cancer type 2 susceptibility protein homolog; DNA repair associated; DNA repair-associated BRCA2; FANCB; Fanconi anemia group D1 protein; Fanconi anemia group D1 protein homolog; mutant BRCA2; mutant DNA repair-associated protein 2; RP11-298P3.4

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Gene Aliases: BRCA2; BRCC2; BROVCA2; FACD; FAD; FAD1; FANCD; FANCD1; GLM3; PNCA2; RAB163; XRCC11

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UniProt ID: (Human) P51587, (Mouse) P97929

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Entrez Gene ID: (Human) 675, (Mouse) 12190, (Rat) 360254

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Function(s)
protease binding DNA binding single-stranded DNA binding histone acetyltransferase activity protein binding H3 histone acetyltransferase activity H4 histone acetyltransferase activity identical protein binding gamma-tubulin binding damaged DNA-binding protein
Process(es)
telomere maintenance via recombination double-strand break repair via homologous recombination oocyte maturation inner cell mass cell proliferation DNA repair nucleotide-excision repair double-strand break repair DNA recombination chromatin remodeling regulation of transcription, DNA-templated cellular response to DNA damage stimulus male meiosis I spermatogenesis brain development cell proliferation female gonad development intrinsic apoptotic signaling pathway in response to DNA damage response to X-ray response to UV-C response to gamma radiation hemopoiesis DNA damage response, signal transduction by p53 class mediator replication fork processing regulation of cytokinesis negative regulation of mammary gland epithelial cell proliferation intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator chordate embryonic development positive regulation of transcription, DNA-templated positive regulation of mitotic cell cycle chromosome organization centrosome duplication establishment of protein localization to telomere hematopoietic stem cell proliferation cellular response to ionizing radiation stem cell proliferation cellular senescence mitotic recombination-dependent replication fork processing regulation of DNA damage checkpoint cytokinesis DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator cell cycle cell aging mammary gland development chromosome breakage homologous chromosome orientation involved in meiotic metaphase I plate congression multicellular organism growth regulation of cell proliferation histone H3 acetylation histone H4 acetylation replication fork protection response to nutrient response to estradiol
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Performance Guarantee

If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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