Immunogen sequence: GSPGNIKDQP RPAFSAIRRN PPMGGNVVIF DTVITNQEEP YQNHSGRFVC TVPGYYYFTF QVLSQWEICL SIVSSSRGQV RRSLGFCDTT NKGLFQVVSG GMVLQLQQGD QVWVEKDPKK GHIYQGSEAD SVFS
C1q is a sub-component of complement C1. C1q associates with complement components C1r and C1s, which are required for the progression of the proteolytic complement cascade. Deficiency of C1q has been associated with lupus erythematosus and glomerulonephritis. C1q is composed of 18 polypeptide chains: six A-chains, six B-chains, and six C-chains. Each chain contains a collagen-like region located near the N terminus and a C-terminal globular region. The A-, B-, and C-chains are arranged in the order A-C-B on chromosome 1.
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Protein Aliases: complement C1q chain A; Complement C1q subcomponent subunit A; complement component 1, q subcomponent, A chain; complement component 1, q subcomponent, alpha polypeptide; complement component C1q, A chain
Gene Aliases: C1QA
UniProt ID: (Human) P02745
Entrez Gene ID: (Human) 712