|Immunocytochemistry (ICC)||20 ug/ml|
|Immunofluorescence (IF)||20 ug/ml|
|Immunohistochemistry (IHC)||5 µg/ml|
|Western Blot (WB)||0.5-1 µg/ml|
|Tested Species reactivity||Human, Mouse|
|Host / Isotype||Rabbit / IgG|
|Immunogen||An 18 amino acid peptide near the carboxy terminus of human CAZIP.|
|Purification||Antigen affinity chromatography|
|Contains||0.02% sodium azide|
|Storage conditions||Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C|
A suggested positive control is A-20 cell lysate.
PA5-20912 can be used with blocking peptide PEP-1026.
CAZIP, also known as TIP150, contains a leucine-zipper domain at the C-terminus and has at least three isoforms. CAZIP is expressed in heart during early cardiac development and in parts of the nervous system in later embryonic development. It is thought to bind microtubules and facilitate the end-binding protein 1 (EB1)-dependent loading of MCAK onto microtubules plus ends and orchestrates the dynamics at the plus end of microtubules. CAZIP may regulate the dynamics of microtubules at their growing distal tip.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: +TIP of 150 kDa; Cardiac zipper protein; Microtubule plus-end tracking protein TIP150; Microtubule-associated tumor suppressor candidate 2; Microtubule-associated tumor suppressor candidate 2 homolog; RP11-274A8.2, CAZIP, KIAA0774, TIP150; Tracking protein of 150 kDa
Gene Aliases: 5730592G18Rik; A730013O20Rik; AU067634; C130038G02Rik; CAZIP; Gm763; ICIS; KIAA0774; mKIAA0774; MTUS2; TIP150
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