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Bethyl Laboratories
CDK5RAP3 Polyclonal Antibody
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FIGURE: 1 / 1
CDK5RAP3 Antibody (A300-871A) in WB
Detection of human CDK5RAP3 by western blot and immunoprecipitation. Samples: Whole cell lysate from HeLa (5, 15 and 50 µg for WB; 1 mg for IP, 20% of IP loaded) and HEK293T (T; 50 µg) cells. Antibodies: Affinity purified rabbit anti-CDK5RAP3 antibody BL3564 (Product # A300-871A) used for WB at 0.1 µg/mL (A) and 1 µg/mL (B) and used for IP at 3 µg/mg lysate (B). CDK5RAP3 was also immunoprecipitated by rabbit anti-CDK5RAP3 antibody BL3563 (Product #A300-870A), which recognizes an upstream epitope. Detection: Chemiluminescence with exposure ... View More
Product Details
A300-871A
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Region between residue 450 and the C-terminus (residue 506) of human CDK5 Regulatory Subunit Associated Protein 3.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Amount
100 µg
Purification
Antigen affinity chromatography
Storage buffer
tris citrate/phosphate, pH 7-8
Contains
0.09% sodium azide
Storage conditions
4°C
Shipping conditions
Ambient (domestic); Wet ice (international)
Product Specific Information
The recommended shelf life for this product is 1 year from date of receipt.
Based on 100% sequence identity, this antibody is predicted to react with Mouse and Orangutan
Target Information
This gene encodes a protein that has been reported to function in signaling pathways governing transcriptional regulation and cell cycle progression. It may play a role in tumorigenesis and metastasis. A pseudogene of this gene is located on the long arm of chromosome 20. Alternative splicing results in multiple transcript variants that encode different isoforms. [provided by RefSeq, May 2013].
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: CDK5 activator-binding protein C53; CDK5 regulatory subunit associated protein IC53-2; CDK5 regulatory subunit-associated protein 3; IC53-2; ischemic heart CDK5 activator-binding protein C53; LXXLL/leucine-zipper-containing ARF-binding protein; LXXLL/leucine-zipper-containing ARFbinding protein; OK/SW-cl.114; Protein HSF-27; unnamed protein product
Gene Aliases: C53; CDK5RAP3; HSF-27; IC53; LZAP; MST016; MSTP016; OK/SW-cl.114; PP1553
UniProt ID: (Human) Q96JB5
Entrez Gene ID: (Human) 80279
regulation of cyclin-dependent protein serine/threonine kinase activity
liver development
negative regulation of protein phosphorylation
mitotic G2 DNA damage checkpoint
regulation of mitotic cell cycle
brain development
blood circulation
cell proliferation
regulation of phosphatase activity
apoptotic nuclear changes
endoplasmic reticulum unfolded protein response
positive regulation of protein ubiquitination
negative regulation of NF-kappaB transcription factor activity
ribosome disassembly
response to endoplasmic reticulum stress
negative regulation of protein catabolic process
negative regulation of MAP kinase activity
negative regulation of protein kinase activity by regulation of protein phosphorylation
mitotic G2/M transition checkpoint
regulation of neuron differentiation
positive regulation of transcription from RNA polymerase II promoter
definitive erythrocyte differentiation
protein ufmylation
negative regulation of protein serine/threonine kinase activity
rescue of stalled ribosome
positive regulation of reticulophagy
positive regulation of protein localization to nucleus
positive regulation of signal transduction by p53 class mediator
positive regulation of proteolysis involved in cellular protein catabolic process
positive regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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