Immunogen sequence: YASQDMEDNV EEIGALQKNP SLGVSNTFTE VLDSALPEES QLSYFNSDEM PAKHTQKSDT EISLE
Highest antigen sequence identity to the following orthologs: Mouse - 48%, Rat - 39%.
Binds unprenylated Rab proteins, presents it to the catalytic component B, and remains bound to it after the geranylgeranyl transfer reaction. The component A may be regenerated by transferring its prenylated Rab to a protein acceptor. Less effective than REP-1 in supporting prenylation of Rab3 family.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: choroideraemia-like protein; choroideremia-like (Rab escort protein 2); Choroideremia-like protein; Rab escort protein 2; Rab proteins geranylgeranyltransferase component A 2; REP-2
Gene Aliases: CHML; REP2
UniProt ID: (Human) P26374
Entrez Gene ID: (Human) 1122