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Proteintech
PLEK Monoclonal Antibody (1D5C2), CoraLite® Plus 488
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Product Details
CL488-66431
Product Specifications
Species Reactivity
Human,
Pig
Host/Isotype
Mouse
/ IgG1
Class
Monoclonal
Type
Antibody
Clone
1D5C2
Immunogen
PLEK fusion protein Ag3187
Conjugate
Excitation/Emission Max
493/522 nm
Form
Liquid
Concentration
1 mg/mL
Amount
100 µg
Purification
Protein G
Storage buffer
PBS, pH 7.3, with 50% glycerol, 0.5% BSA
Contains
0.05% ProClin 300
Storage conditions
-20°C, store in dark
Shipping conditions
Wet ice
Product Specific Information
Immunogen sequence: MEPKRIREG YLVKKGSVFN TWKPMWVVLL EDGIEFYKKK SDNSPKGMIP LKGSTLTSPC QDFGKRMFVF KITTTKQQDH FFQAAFLEER DAWVRDIKKA IKCIEGGQKF ARKSTRRSIR LPETIDLGAL YLSMKDTEKG IKELNLEKDK KIFNHCFTGN CVIDWLVSNQ SVRNRQEGLM IASSLLNEGY LQPAGDMSKS AVDGTAENPF LDNPDAFYYF PDSGFFCEEN SSDDDVILKE EFRGVIIKQG CLLKQGHRRK NWKVRKFILR EDPAYLHYYD PAGAEDPLGA IHLRGCVVTS VESNSNGRKS EEENLFEIIT ADEVHYFLQA ATPKERTEWI KAIQMASRTG K
Target Information
Major protein kinase C substrate of platelets.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: FLJ27168; p47; Platelet 47 kDa protein; Pleckstrin; PLEK; unnamed protein product
Gene Aliases: P47; PLEK; PLEK1
UniProt ID: (Human) P08567
Entrez Gene ID: (Pig) 100516257, (Human) 5341
hematopoietic progenitor cell differentiation
platelet degranulation
vesicle docking involved in exocytosis
phospholipase C-activating G-protein coupled receptor signaling pathway
integrin-mediated signaling pathway
positive regulation of platelet activation
negative regulation of inositol phosphate biosynthetic process
cell projection organization
actin cytoskeleton organization
positive regulation of actin filament depolymerization
phospholipase C-inhibiting G-protein coupled receptor signaling pathway
cortical actin cytoskeleton organization
ruffle organization
positive regulation of actin filament bundle assembly
positive regulation of integrin activation
intracellular signal transduction
inositol phosphate metabolic process
positive regulation of cellular component biogenesis
negative regulation of G-protein coupled receptor protein signaling pathway
negative regulation of calcium-mediated signaling
regulation of cell diameter
thrombin receptor signaling pathway
negative regulation of thrombin receptor signaling pathway
platelet aggregation
protein secretion by platelet
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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