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Proteintech
U2AF2/U2AF65 Monoclonal Antibody (1B7E7), CoraLite® Plus 488
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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Product Details
CL488-68166
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Mouse
/ IgG2a
Class
Monoclonal
Type
Antibody
Clone
1B7E7
Immunogen
U2AF2/U2AF65 fusion protein Ag8070
Conjugate
CoraLite® Plus 488
CoraLite® Plus 488
CoraLite® Plus 488
Excitation/Emission Max
493/522 nm
Form
Liquid
Concentration
1 mg/mL
Amount
100 µg
Purification
Protein A
Storage buffer
PBS, pH 7.3, with 50% glycerol, 0.5% BSA
Contains
0.05% ProClin 300
Storage conditions
-20°C, store in dark
Shipping conditions
Wet ice
Product Specific Information
Immunogen sequence: IPATALLPT MTPDGLAVTP TPVPVVGSQM TRQARRLYVG NIPFGITEEA MMDFFNAQMR LGGLTQAPGN PVLAVQINQD KNFAFLEFRS VDETTQAMAF DGIIFQGQSL KIRRPHDYQP LPGMSENPSV YVPGVVSTVV PDSAHKLFIG GLPNYLNDDQ VKELLTSFGP LKAFNLVKDS ATGLSKGYAF CEYVDINVTD QAIAGLNGMQ LGDKKLLVQR ASVGAKNATL STINQTPVTL QVPGLMSSQV QMGGHPTEVL CLMNMVLPEE LLDDEEYEEI VEDVRDECSK YGLVKSIEIP RPVDGVEVPG CGKIFVEFTS VFDCQKAMQG LTGRKFANRV VVTKYCDPDS YHRRDFW
Target Information
U2 auxiliary factor (U2AF), comprised of a large and a small subunit, is a non-snRNP protein required for the binding of U2 snRNP to the pre-mRNA branch site. This gene encodes the U2AF large subunit which contains a sequence-specific RNA-binding region with 3 RNA recognition motifs and an Arg/Ser-rich domain necessary for splicing. The large subunit binds to the polypyrimidine tract of introns early during spliceosome assembly. Multiple transcript variants have been detected for this gene, but the full-length natures of only two have been determined to date.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: hU2AF65; U2 (RNU2) small nuclear RNA auxiliary factor 2; U2 auxiliary factor 65 kDa subunit; U2 small nuclear ribonucleoprotein auxiliary factor (65kD); U2 small nuclear ribonucleoprotein auxiliary factor (U2AF) 2; U2 small nuclear ribonucleoprotein auxiliary factor (U2AF), 65 kDa; U2 snRNP auxiliary factor large subunit; unnamed protein product
Gene Aliases: 65kDa; DEVDFB; U2AF65
UniProt ID: (Human) P26368, (Mouse) P26369
Entrez Gene ID: (Human) 11338, (Rat) 308335, (Mouse) 22185
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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